Analysis of CT features of 15 children with 2019 novel coronavirus infection
Objective: To explore imaging characteristics of children with 2019 novel coronavirus (2019-nCoV) infection. Methods: A retrospective analysis was performed on clinical data and chest CT images of 15 children diagnosed with 2019-nCoV infection. They were admitted to the Third People's Hospital of Shenzhen from January 16 to February 6, 2020. The distribution and morphology of pulmonary lesions on chest CT images were analyzed. Results: Among the 15 children, 5 were males and 10 females, aged from 4 to 14 years. Five of the 15 children were febrile and 10 were asymptomatic on the first visit. The first nasal or pharyngeal swab samples in all the 15 cases were positive for 2019-nCoV nucleic acid. For their first chest CT images, 6 patients had no lesions, while 9 patients had pulmonary inflammatory lesions. Seven cases had small nodular ground glass opacities and 2 cases had speckled ground glass opacities. After 3 to 5 days of treatment, 2019-nCoV nucleic acid in a second respiratory sample turned negative in 6 cases. Among them, chest CT images showed less lesions in 2 cases, no lesion in 3 cases, and no improvement in 1 case. The remaining 9 cases were still positive in a second nucleic acid test. Six patients showed similar chest CT inflammation, while 3 patients had new lesions, which were all small nodular ground glass opacities. Conclusions: The early chest CT images of children with 2019-nCoV infection are mostly small nodular ground glass opacities. The clinical symptoms of children with 2019-nCoV infection are nonspecific. Dynamic reexamination of chest CT and nucleic acid are important.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:58 |
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| Enthalten in: |
Zhonghua er ke za zhi = Chinese journal of pediatrics - 58(2020), 4 vom: 02. Apr., Seite 275-278 |
| Sprache: |
Chinesisch |
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| Beteiligte Personen: |
Feng, K [VerfasserIn] |
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| Links: |
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| Themen: |
2019-novel coronavirus |
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| Anmerkungen: |
Date Completed 03.04.2020 Date Revised 18.12.2020 published: Print Citation Status MEDLINE |
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| doi: |
10.3760/cma.j.cn112140-20200210-00071 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM308197062 |
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| 245 | 1 | 0 | |a Analysis of CT features of 15 children with 2019 novel coronavirus infection |
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| 500 | |a Date Completed 03.04.2020 | ||
| 500 | |a Date Revised 18.12.2020 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Objective: To explore imaging characteristics of children with 2019 novel coronavirus (2019-nCoV) infection. Methods: A retrospective analysis was performed on clinical data and chest CT images of 15 children diagnosed with 2019-nCoV infection. They were admitted to the Third People's Hospital of Shenzhen from January 16 to February 6, 2020. The distribution and morphology of pulmonary lesions on chest CT images were analyzed. Results: Among the 15 children, 5 were males and 10 females, aged from 4 to 14 years. Five of the 15 children were febrile and 10 were asymptomatic on the first visit. The first nasal or pharyngeal swab samples in all the 15 cases were positive for 2019-nCoV nucleic acid. For their first chest CT images, 6 patients had no lesions, while 9 patients had pulmonary inflammatory lesions. Seven cases had small nodular ground glass opacities and 2 cases had speckled ground glass opacities. After 3 to 5 days of treatment, 2019-nCoV nucleic acid in a second respiratory sample turned negative in 6 cases. Among them, chest CT images showed less lesions in 2 cases, no lesion in 3 cases, and no improvement in 1 case. The remaining 9 cases were still positive in a second nucleic acid test. Six patients showed similar chest CT inflammation, while 3 patients had new lesions, which were all small nodular ground glass opacities. Conclusions: The early chest CT images of children with 2019-nCoV infection are mostly small nodular ground glass opacities. The clinical symptoms of children with 2019-nCoV infection are nonspecific. Dynamic reexamination of chest CT and nucleic acid are important | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a 2019-novel coronavirus | |
| 650 | 4 | |a Child | |
| 650 | 4 | |a Tomography, X-ray computed | |
| 650 | 7 | |a RNA, Viral |2 NLM | |
| 700 | 1 | |a Yun, Y X |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, X F |e verfasserin |4 aut | |
| 700 | 1 | |a Yang, G D |e verfasserin |4 aut | |
| 700 | 1 | |a Zheng, Y J |e verfasserin |4 aut | |
| 700 | 1 | |a Lin, C M |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, L F |e verfasserin |4 aut | |
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