Analysis of heart injury laboratory parameters in 273 COVID-19 patients in one hospital in Wuhan, China
© 2020 Wiley Periodicals, Inc..
An outbreak of severe acute respiratory syndrome novel coronavirus (SARS-CoV-2) epidemic spreads rapidly worldwide. SARS-CoV-2 infection caused mildly to seriously and fatally respiratory, enteric, cardiovascular, and neurological diseases. In this study, we detected and analyzed the main laboratory indicators related to heart injury, creatine kinase isoenzyme-MB (CK-MB), myohemoglobin (MYO), cardiac troponin I (ultra-TnI), and N-terminal pro-brain natriuretic peptide (NT-proBNP), in 273 patients with COVID-19 and investigated the correlation between heart injury and severity of the disease. It was found that higher concentration in venous blood of CK-MB, MYO, ultra-TnI, and NT-proBNP were associated with the severity and case fatality rate of COVID-19. Careful monitoring of the myocardiac enzyme profiles is of great importance in reducing the complications and mortality in patients with COVID-19.
| Errataetall: |
CommentIn: J Med Virol. 2020 Oct;92(10):1747. - PMID 32267000 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:92 |
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| Enthalten in: |
Journal of medical virology - 92(2020), 7 vom: 17. Juli, Seite 819-823 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Han, Huan [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 24.06.2020 Date Revised 16.07.2022 published: Print-Electronic CommentIn: J Med Virol. 2020 Oct;92(10):1747. - PMID 32267000 Citation Status MEDLINE |
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| doi: |
10.1002/jmv.25809 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM308185706 |
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2020 Wiley Periodicals, Inc. | ||
| 520 | |a An outbreak of severe acute respiratory syndrome novel coronavirus (SARS-CoV-2) epidemic spreads rapidly worldwide. SARS-CoV-2 infection caused mildly to seriously and fatally respiratory, enteric, cardiovascular, and neurological diseases. In this study, we detected and analyzed the main laboratory indicators related to heart injury, creatine kinase isoenzyme-MB (CK-MB), myohemoglobin (MYO), cardiac troponin I (ultra-TnI), and N-terminal pro-brain natriuretic peptide (NT-proBNP), in 273 patients with COVID-19 and investigated the correlation between heart injury and severity of the disease. It was found that higher concentration in venous blood of CK-MB, MYO, ultra-TnI, and NT-proBNP were associated with the severity and case fatality rate of COVID-19. Careful monitoring of the myocardiac enzyme profiles is of great importance in reducing the complications and mortality in patients with COVID-19 | ||
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| 700 | 1 | |a Yang, Jie |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Fang |e verfasserin |4 aut | |
| 700 | 1 | |a Wu, Kailang |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Lang |e verfasserin |4 aut | |
| 700 | 1 | |a Hou, Wei |e verfasserin |4 aut | |
| 700 | 1 | |a Feng, Yong |e verfasserin |4 aut | |
| 700 | 1 | |a Zhu, Chengliang |e verfasserin |4 aut | |
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