Short term olfactory memory and olfactory function after inhalation anesthetic agents : a randomized clinical trial

Copyright © 2020 Sociedade Brasileira de Anestesiologia. Publicado por Elsevier Editora Ltda. All rights reserved..

BACKGROUND AND OBJECTIVES: This clinical trial aimed to evaluate the effects of two different inhalation anesthetic agents on postoperative olfactory memory and olfactory function in patients who underwent micro laryngeal surgery.

METHODS: This randomized prospective controlled study consisted of 102 consecutive patients with a voice disorder. The patients underwent micro laryngeal surgery for voice disorders under general anesthesia. Patients who did not meet inclusion criteria and/or declined to participate (n=34) were excluded from the study. Patients were divided into two groups. Four patients from Group 1 and four patients from Group 2 were lost to follow-up. Group 1 (n=30) received sevoflurane, and Group 2 (n=30) received desflurane during anesthesia. We compared the results by performing the pre-op and post-op Connecticut Chemosensory Clinical Research Center Olfactory test.

RESULTS: Thirty-three patients (55%) were male and 27 (45%) were female. The mean age was 48.18±13.88 years (range: 19-70 years). Preoperative and postoperative olfactory functions did not show a significant difference within the groups postoperatively (p> 0.05). Preoperative and postoperative olfactory memory showed a significant decrease 3hours after the surgery (p <0.05).

CONCLUSIONS: Olfactory functions and memory were not affected by desflurane in the early postoperative period. Although sevoflurane did not affect olfactory functions, it had a temporary negative effect on olfactory memory in the early postoperative period.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:70

Enthalten in:

Brazilian journal of anesthesiology (Elsevier) - 70(2020), 1 vom: 01. Jan., Seite 36-41

Sprache:

Portugiesisch

Weiterer Titel:

Memória olfativa de curta duração e função olfativa após anestésicos inalatórios: estudo clínico randomizado

Beteiligte Personen:

Sari, Huseyin [VerfasserIn]
Atar, Yavuz [VerfasserIn]
Mingir, Tarkan [VerfasserIn]
Kumral, Tolgar Lutfi [VerfasserIn]
Akgun, Muhammed Fatih [VerfasserIn]
Ahmed, Esmail Abdulahi [VerfasserIn]
Aydogdu, Imran [VerfasserIn]
Salturk, Ziya [VerfasserIn]
Berkiten, Guler [VerfasserIn]
Uyar, Yavuz [VerfasserIn]

Links:

Volltext

Themen:

38LVP0K73A
Anestesia inalatória
Anesthetics, Inhalation
CRS35BZ94Q
Comparative Study
Desflurane
Desflurano
Inhalation anesthesia
Journal Article
Memória olfativa
Olfactory memory
Randomized Controlled Trial
Sevoflurane
Sevoflurano

Anmerkungen:

Date Completed 14.05.2021

Date Revised 16.08.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.bjan.2019.12.005

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM307610276