Snapshot evaluation of acute and chronic heart failure in real-life in Turkey : A follow-up data for mortality
OBJECTIVE: Heart failure (HF) is a progressive clinical syndrome. SELFIE-TR is a registry illustrating the overall HF patient profile of Turkey. Herein, all-cause mortality (ACM) data during follow-up were provided.
METHODS: This is a prospective outcome analysis of SELFIE-TR. Patients were classified as acute HF (AHF) versus chronic HF (CHF) and HF with reduced ejection fraction (HFrEF), HF with mid-range ejection fraction, and HF with preserved ejection fraction and were followed up for ACM.
RESULTS: There were 1054 patients with a mean age of 63.3±13.3 years and with a median follow-up period of 16 (7-17) months. Survival data within 1 year were available in 1022 patients. Crude ACM was 19.9% for 1 year in the whole group. ACM within 1 year was 13.7% versus 32.6% in patients with CHF and AHF, respectively (p<0.001). Angiotensin-converting enzyme inhibitor/angiotensin receptor blocker, beta blocker, and mineralocorticoid receptor antagonist were present in 70.6%, 88.2%, and 50.7%, respectively. In the whole cohort, survival curves were graded according to guideline-directed medical therapy (GDMT) scores ≤1 versus 2 versus 3 as 28% versus 20.2% versus 12.2%, respectively (p<0.001). Multivariate analysis of the whole cohort yielded age (p=0.009) and AHF (p=0.028) as independent predictors of mortality in 1 year.
CONCLUSION: One-year mortality is high in Turkish patients with HF compared with contemporary cohorts with AHF and CHF. Of note, GDMT score is influential on 1-year mortality being the most striking one on chronic HFrEF. On the other hand, in the whole cohort, age and AHF were the only independent predictors of death in 1 year.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:23 |
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| Enthalten in: |
Anatolian journal of cardiology - 23(2020), 3 vom: 01. Feb., Seite 160-168 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Yılmaz, Mehmet Birhan [VerfasserIn] |
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| Links: |
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| Themen: |
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| Anmerkungen: |
Date Completed 23.11.2020 Date Revised 28.05.2021 published: Print Citation Status MEDLINE |
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| doi: |
10.14744/AnatolJCardiol.2019.87894 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM307121763 |
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| 100 | 1 | |a Yılmaz, Mehmet Birhan |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Snapshot evaluation of acute and chronic heart failure in real-life in Turkey |b A follow-up data for mortality |
| 264 | 1 | |c 2020 | |
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| 500 | |a Date Completed 23.11.2020 | ||
| 500 | |a Date Revised 28.05.2021 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVE: Heart failure (HF) is a progressive clinical syndrome. SELFIE-TR is a registry illustrating the overall HF patient profile of Turkey. Herein, all-cause mortality (ACM) data during follow-up were provided | ||
| 520 | |a METHODS: This is a prospective outcome analysis of SELFIE-TR. Patients were classified as acute HF (AHF) versus chronic HF (CHF) and HF with reduced ejection fraction (HFrEF), HF with mid-range ejection fraction, and HF with preserved ejection fraction and were followed up for ACM | ||
| 520 | |a RESULTS: There were 1054 patients with a mean age of 63.3±13.3 years and with a median follow-up period of 16 (7-17) months. Survival data within 1 year were available in 1022 patients. Crude ACM was 19.9% for 1 year in the whole group. ACM within 1 year was 13.7% versus 32.6% in patients with CHF and AHF, respectively (p<0.001). Angiotensin-converting enzyme inhibitor/angiotensin receptor blocker, beta blocker, and mineralocorticoid receptor antagonist were present in 70.6%, 88.2%, and 50.7%, respectively. In the whole cohort, survival curves were graded according to guideline-directed medical therapy (GDMT) scores ≤1 versus 2 versus 3 as 28% versus 20.2% versus 12.2%, respectively (p<0.001). Multivariate analysis of the whole cohort yielded age (p=0.009) and AHF (p=0.028) as independent predictors of mortality in 1 year | ||
| 520 | |a CONCLUSION: One-year mortality is high in Turkish patients with HF compared with contemporary cohorts with AHF and CHF. Of note, GDMT score is influential on 1-year mortality being the most striking one on chronic HFrEF. On the other hand, in the whole cohort, age and AHF were the only independent predictors of death in 1 year | ||
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Aksakal, Emrah |e verfasserin |4 aut | |
| 700 | 1 | |a Aksu, Uğur |e verfasserin |4 aut | |
| 700 | 1 | |a Altay, Hakan |e verfasserin |4 aut | |
| 700 | 1 | |a Nesligül, Yıldırım |e verfasserin |4 aut | |
| 700 | 1 | |a Çelik, Ahmet |e verfasserin |4 aut | |
| 700 | 1 | |a Akil, Mehmet Ata |e verfasserin |4 aut | |
| 700 | 1 | |a Bekar, Lütfü |e verfasserin |4 aut | |
| 700 | 1 | |a Vural, Mustafa Gökhan |e verfasserin |4 aut | |
| 700 | 1 | |a Çetin Güvenç, Rengin |e verfasserin |4 aut | |
| 700 | 1 | |a Özer, Savaş |e verfasserin |4 aut | |
| 700 | 1 | |a Ural, Dilek |e verfasserin |4 aut | |
| 700 | 1 | |a Çavuşoğlu, Yüksel |e verfasserin |4 aut | |
| 700 | 1 | |a Tokgözoğlu, Lale |e verfasserin |4 aut | |
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| 773 | 1 | 8 | |g volume:23 |g year:2020 |g number:3 |g day:01 |g month:02 |g pages:160-168 |
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