Palladium-Catalyzed β-Arylation of Cyclic α,β-Unsaturated O-Methyl Oximes with Aryl Iodides
We report a Pd-catalyzed β-arylation of cyclic α,β-unsaturated O-methyl oximes with aryl iodides. This reaction shows complete regioselectivity and excellent functional group tolerance. β-Arylation of 2-cyclohexen-1-one O-methyl oxime (existing as 2 : 1 E/Z mixture) with certain aryl iodides such as 4-iodoanisole affords only β-arylated (E)-O-methyl oximes.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:68 |
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| Enthalten in: |
Chemical & pharmaceutical bulletin - 68(2020), 3 vom: 31., Seite 288-291 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Akagi, Yusuke [VerfasserIn] |
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| Links: |
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| Themen: |
β-arylation |
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| Anmerkungen: |
Date Completed 20.04.2020 Date Revised 20.04.2020 published: Print Citation Status MEDLINE |
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| doi: |
10.1248/cpb.c19-01012 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM307076733 |
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| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a We report a Pd-catalyzed β-arylation of cyclic α,β-unsaturated O-methyl oximes with aryl iodides. This reaction shows complete regioselectivity and excellent functional group tolerance. β-Arylation of 2-cyclohexen-1-one O-methyl oxime (existing as 2 : 1 E/Z mixture) with certain aryl iodides such as 4-iodoanisole affords only β-arylated (E)-O-methyl oximes | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Fujiwara–Moritani reaction | |
| 650 | 4 | |a O-methyl oxime | |
| 650 | 4 | |a aryl iodide | |
| 650 | 4 | |a palladium | |
| 650 | 4 | |a β-arylation | |
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| 700 | 1 | |a Fukuyama, Shiori |e verfasserin |4 aut | |
| 700 | 1 | |a Komatsu, Toshiya |e verfasserin |4 aut | |
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