Virus Isolation from the First Patient with SARS-CoV-2 in Korea
© 2020 The Korean Academy of Medical Sciences..
Novel coronavirus (SARS-CoV-2) is found to cause a large outbreak started from Wuhan since December 2019 in China and SARS-CoV-2 infections have been reported with epidemiological linkage to China in 25 countries until now. We isolated SARS-CoV-2 from the oropharyngeal sample obtained from the patient with the first laboratory-confirmed SARS-CoV-2 infection in Korea. Cytopathic effects of SARS-CoV-2 in the Vero cell cultures were confluent 3 days after the first blind passage of the sample. Coronavirus was confirmed with spherical particle having a fringe reminiscent of crown on transmission electron microscopy. Phylogenetic analyses of whole genome sequences showed that it clustered with other SARS-CoV-2 reported from Wuhan.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:35 |
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| Enthalten in: |
Journal of Korean medical science - 35(2020), 7 vom: 24. Feb., Seite e84 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Park, Wan Beom [VerfasserIn] |
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| Links: |
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| Themen: |
2019 Novel Coronavirus |
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| Anmerkungen: |
Date Completed 16.03.2020 Date Revised 18.12.2020 published: Electronic Citation Status MEDLINE |
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| doi: |
10.3346/jkms.2020.35.e84 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM306746263 |
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| 520 | |a Novel coronavirus (SARS-CoV-2) is found to cause a large outbreak started from Wuhan since December 2019 in China and SARS-CoV-2 infections have been reported with epidemiological linkage to China in 25 countries until now. We isolated SARS-CoV-2 from the oropharyngeal sample obtained from the patient with the first laboratory-confirmed SARS-CoV-2 infection in Korea. Cytopathic effects of SARS-CoV-2 in the Vero cell cultures were confluent 3 days after the first blind passage of the sample. Coronavirus was confirmed with spherical particle having a fringe reminiscent of crown on transmission electron microscopy. Phylogenetic analyses of whole genome sequences showed that it clustered with other SARS-CoV-2 reported from Wuhan | ||
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| 700 | 1 | |a Kang, Chang Kyung |e verfasserin |4 aut | |
| 700 | 1 | |a Choe, Pyoeng Gyun |e verfasserin |4 aut | |
| 700 | 1 | |a Kim, Jin Yong |e verfasserin |4 aut | |
| 700 | 1 | |a Yun, Jiyoung |e verfasserin |4 aut | |
| 700 | 1 | |a Lee, Gir Won |e verfasserin |4 aut | |
| 700 | 1 | |a Seong, Moon Woo |e verfasserin |4 aut | |
| 700 | 1 | |a Kim, Nam Joong |e verfasserin |4 aut | |
| 700 | 1 | |a Seo, Jeong Sun |e verfasserin |4 aut | |
| 700 | 1 | |a Oh, Myoung Don |e verfasserin |4 aut | |
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