Adrenocorticotropic Hormone-Producing Paraganglioma With Low Plasma ACTH Level : A Case Report and Review of the Literature
Copyright © 2020 Liu, Liu, Chen, Xu and Yuan..
Ectopic adrenocorticotropic hormone (ACTH) syndrome caused by paraganglioma is extremely rare. It usually accompanied by high or normal plasma ACTH level. Here we described a male who presented with ectopic ACTH-producing paraganglioma and a low plasma ACTH level. Immunohistochemistry and immunofluorescence confirmed ACTH production in focal paraganglioma cells. This unusual case expanded the spectrum of ACTH-dependent Cushing's syndrome and revealed a potential mechanism of this unique clinical phenotype. Besides, the literature concerning ACTH-producing paraganglioma is reviewed.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2019 |
|---|---|
| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:10 |
|---|---|
| Enthalten in: |
Frontiers in endocrinology - 10(2019) vom: 03., Seite 936 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Liu, Siyue [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Adrenocorticotropic hormone |
|---|
| Anmerkungen: |
Date Revised 14.02.2020 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
|---|
| doi: |
10.3389/fendo.2019.00936 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM306330466 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM306330466 | ||
| 003 | DE-627 | ||
| 005 | 20231225123131.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2019 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.3389/fendo.2019.00936 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1021.xml |
| 035 | |a (DE-627)NLM306330466 | ||
| 035 | |a (NLM)32038491 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Liu, Siyue |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Adrenocorticotropic Hormone-Producing Paraganglioma With Low Plasma ACTH Level |b A Case Report and Review of the Literature |
| 264 | 1 | |c 2019 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Revised 14.02.2020 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a Copyright © 2020 Liu, Liu, Chen, Xu and Yuan. | ||
| 520 | |a Ectopic adrenocorticotropic hormone (ACTH) syndrome caused by paraganglioma is extremely rare. It usually accompanied by high or normal plasma ACTH level. Here we described a male who presented with ectopic ACTH-producing paraganglioma and a low plasma ACTH level. Immunohistochemistry and immunofluorescence confirmed ACTH production in focal paraganglioma cells. This unusual case expanded the spectrum of ACTH-dependent Cushing's syndrome and revealed a potential mechanism of this unique clinical phenotype. Besides, the literature concerning ACTH-producing paraganglioma is reviewed | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Cushing's syndrome | |
| 650 | 4 | |a adrenocorticotropic hormone | |
| 650 | 4 | |a ectopic ACTH syndrome | |
| 650 | 4 | |a immunofluorescence | |
| 650 | 4 | |a immunohistochemistry | |
| 650 | 4 | |a paraganglioma | |
| 700 | 1 | |a Liu, Zhelong |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Fuqiong |e verfasserin |4 aut | |
| 700 | 1 | |a Xu, Weijie |e verfasserin |4 aut | |
| 700 | 1 | |a Yuan, Gang |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Frontiers in endocrinology |d 2010 |g 10(2019) vom: 03., Seite 936 |w (DE-627)NLM208813357 |x 1664-2392 |7 nnns |
| 773 | 1 | 8 | |g volume:10 |g year:2019 |g day:03 |g pages:936 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.3389/fendo.2019.00936 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 10 |j 2019 |b 03 |h 936 | ||