Clinical characteristics and therapeutic procedure for four cases with 2019 novel coronavirus pneumonia receiving combined Chinese and Western medicine treatment

Pneumonia associated with the 2019 novel coronavirus (2019-nCoV) is continuously and rapidly circulating at present. No effective antiviral treatment has been verified thus far. We report here the clinical characteristics and therapeutic procedure for four patients with mild or severe 2019-nCoV pneumonia admitted to Shanghai Public Health Clinical Center. All the patients were given antiviral treatment including lopinavir/ritonavir (Kaletra®), arbidol, and Shufeng Jiedu Capsule (SFJDC, a traditional Chinese medicine) and other necessary support care. After treatment, three patients gained significant improvement in pneumonia associated symptoms, two of whom were confirmed 2019-nCoV negative and discharged, and one of whom was virus negative at the first test. The remaining patient with severe pneumonia had shown signs of improvement by the cutoff date for data collection. Results obtained in the current study may provide clues for treatment of 2019-nCoV pneumonia. The efficacy of antiviral treatment including lopinavir/ritonavir, arbidol, and SFJDC warrants further verification in future study.

Errataetall:

ErratumIn: Biosci Trends. 2020;14(1):E1. - PMID 32238667

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:14

Enthalten in:

Bioscience trends - 14(2020), 1 vom: 16. März, Seite 64-68

Sprache:

Englisch

Beteiligte Personen:

Wang, Zhenwei [VerfasserIn]
Chen, Xiaorong [VerfasserIn]
Lu, Yunfei [VerfasserIn]
Chen, Feifei [VerfasserIn]
Zhang, Wei [VerfasserIn]

Links:

Volltext

Themen:

2019-nCoV
2494G1JF75
93M09WW4RU
Antiviral Agents
Arbidol
Case Reports
Drug Combinations
Drugs, Chinese Herbal
Indoles
Journal Article
Lopinavir
Lopinavir-ritonavir drug combination
O3J8G9O825
Ritonavir
Shufeng Jiedu Capsule
Shufeng jiedu
Umifenovir

Anmerkungen:

Date Completed 18.03.2020

Date Revised 07.12.2022

published: Print-Electronic

ErratumIn: Biosci Trends. 2020;14(1):E1. - PMID 32238667

Citation Status MEDLINE

doi:

10.5582/bst.2020.01030

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM306319497