Assessment of dynamic cerebral autoregulation in humans : Is reproducibility dependent on blood pressure variability?
We tested the influence of blood pressure variability on the reproducibility of dynamic cerebral autoregulation (DCA) estimates. Data were analyzed from the 2nd CARNet bootstrap initiative, where mean arterial blood pressure (MABP), cerebral blood flow velocity (CBFV) and end tidal CO2 were measured twice in 75 healthy subjects. DCA was analyzed by 14 different centers with a variety of different analysis methods. Intraclass Correlation (ICC) values increased significantly when subjects with low power spectral density MABP (PSD-MABP) values were removed from the analysis for all gain, phase and autoregulation index (ARI) parameters. Gain in the low frequency band (LF) had the highest ICC, followed by phase LF and gain in the very low frequency band. No significant differences were found between analysis methods for gain parameters, but for phase and ARI parameters, significant differences between the analysis methods were found. Alternatively, the Spearman-Brown prediction formula indicated that prolongation of the measurement duration up to 35 minutes may be needed to achieve good reproducibility for some DCA parameters. We conclude that poor DCA reproducibility (ICC<0.4) can improve to good (ICC > 0.6) values when cases with low PSD-MABP are removed, and probably also when measurement duration is increased.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2020 |
|---|---|
| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:15 |
|---|---|
| Enthalten in: |
PloS one - 15(2020), 1 vom: 24., Seite e0227651 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Elting, Jan Willem [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
|---|
| Anmerkungen: |
Date Completed 10.04.2020 Date Revised 17.12.2020 published: Electronic-eCollection Citation Status MEDLINE |
|---|
| doi: |
10.1371/journal.pone.0227651 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM30523112X |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM30523112X | ||
| 003 | DE-627 | ||
| 005 | 20231225120726.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2020 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1371/journal.pone.0227651 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1017.xml |
| 035 | |a (DE-627)NLM30523112X | ||
| 035 | |a (NLM)31923919 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Elting, Jan Willem |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Assessment of dynamic cerebral autoregulation in humans |b Is reproducibility dependent on blood pressure variability? |
| 264 | 1 | |c 2020 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 10.04.2020 | ||
| 500 | |a Date Revised 17.12.2020 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a We tested the influence of blood pressure variability on the reproducibility of dynamic cerebral autoregulation (DCA) estimates. Data were analyzed from the 2nd CARNet bootstrap initiative, where mean arterial blood pressure (MABP), cerebral blood flow velocity (CBFV) and end tidal CO2 were measured twice in 75 healthy subjects. DCA was analyzed by 14 different centers with a variety of different analysis methods. Intraclass Correlation (ICC) values increased significantly when subjects with low power spectral density MABP (PSD-MABP) values were removed from the analysis for all gain, phase and autoregulation index (ARI) parameters. Gain in the low frequency band (LF) had the highest ICC, followed by phase LF and gain in the very low frequency band. No significant differences were found between analysis methods for gain parameters, but for phase and ARI parameters, significant differences between the analysis methods were found. Alternatively, the Spearman-Brown prediction formula indicated that prolongation of the measurement duration up to 35 minutes may be needed to achieve good reproducibility for some DCA parameters. We conclude that poor DCA reproducibility (ICC<0.4) can improve to good (ICC > 0.6) values when cases with low PSD-MABP are removed, and probably also when measurement duration is increased | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Multicenter Study | |
| 700 | 1 | |a Sanders, Marit L |e verfasserin |4 aut | |
| 700 | 1 | |a Panerai, Ronney B |e verfasserin |4 aut | |
| 700 | 1 | |a Aries, Marcel |e verfasserin |4 aut | |
| 700 | 1 | |a Bor-Seng-Shu, Edson |e verfasserin |4 aut | |
| 700 | 1 | |a Caicedo, Alexander |e verfasserin |4 aut | |
| 700 | 1 | |a Chacon, Max |e verfasserin |4 aut | |
| 700 | 1 | |a Gommer, Erik D |e verfasserin |4 aut | |
| 700 | 1 | |a Van Huffel, Sabine |e verfasserin |4 aut | |
| 700 | 1 | |a Jara, José L |e verfasserin |4 aut | |
| 700 | 1 | |a Kostoglou, Kyriaki |e verfasserin |4 aut | |
| 700 | 1 | |a Mahdi, Adam |e verfasserin |4 aut | |
| 700 | 1 | |a Marmarelis, Vasilis Z |e verfasserin |4 aut | |
| 700 | 1 | |a Mitsis, Georgios D |e verfasserin |4 aut | |
| 700 | 1 | |a Müller, Martin |e verfasserin |4 aut | |
| 700 | 1 | |a Nikolic, Dragana |e verfasserin |4 aut | |
| 700 | 1 | |a Nogueira, Ricardo C |e verfasserin |4 aut | |
| 700 | 1 | |a Payne, Stephen J |e verfasserin |4 aut | |
| 700 | 1 | |a Puppo, Corina |e verfasserin |4 aut | |
| 700 | 1 | |a Shin, Dae C |e verfasserin |4 aut | |
| 700 | 1 | |a Simpson, David M |e verfasserin |4 aut | |
| 700 | 1 | |a Tarumi, Takashi |e verfasserin |4 aut | |
| 700 | 1 | |a Yelicich, Bernardo |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Rong |e verfasserin |4 aut | |
| 700 | 1 | |a Claassen, Jurgen A H R |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t PloS one |d 2006 |g 15(2020), 1 vom: 24., Seite e0227651 |w (DE-627)NLM167327399 |x 1932-6203 |7 nnns |
| 773 | 1 | 8 | |g volume:15 |g year:2020 |g number:1 |g day:24 |g pages:e0227651 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1371/journal.pone.0227651 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 15 |j 2020 |e 1 |b 24 |h e0227651 | ||