The assessment of the peak of reflex cough in subjects with acquired brain injury and tracheostomy and healthy controls
Copyright © 2019 Elsevier B.V. All rights reserved..
INTRODUCTION: There is no standard procedure to evaluated the peak of reflex cough flow (PCF-reflex) in the literature, which is important assessment in subjects with acquired brain injury and tracheostomy cannula. The present study aims to investigate the PCF of the reflex cough in a broad sample of healthy controls and, furthermore, the presence and the strength of voluntary and reflex cough in subjects with ABI with tracheostomy cannula.
MATERIALS AND METHODS: We recruited 147 participants including the healthy subjects (n = 105) and acquired brain injury subjects (n = 43), who underwent respiratory assessment: the Tidal Volume, Forced Vital Capacity, PCF of voluntary cough (PCF-voluntary) and PCF-reflex (using a spirometer connected with a nebulizer by a bidirectional).
RESULTS: The PCF-reflex of controls and subjects was significant lower than the PCF-voluntary (P < 0.01). The PCF-voluntary was not assessed in 26 (60.5 %) subjects due to severe cognitive deficit. In subjects without cognitive deficits (n = 17; 39.5 %), it was significantly lower than in healthy controls (p < 0.01). In contrast, the PCF-reflex was completed in all subjects and it was not significantly different from healthy controls. Furthermore, the strength of the PCF-reflex decreased with increasing inhalation numbers of nebulised air.
CONCLUSION: Reflex cough behaviour differs largely from voluntary cough and the PCF results reflect this great discrepancy. PCF-reflex could be useful parameter for assessing the airway protection whereas PCF-voluntary for measuring airway clearance.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:274 |
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| Enthalten in: |
Respiratory physiology & neurobiology - 274(2020) vom: 20. März, Seite 103356 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Enrichi, Claudia [VerfasserIn] |
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| Anmerkungen: |
Date Completed 12.04.2021 Date Revised 12.04.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.resp.2019.103356 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM304989401 |
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| 245 | 1 | 4 | |a The assessment of the peak of reflex cough in subjects with acquired brain injury and tracheostomy and healthy controls |
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| 500 | |a Date Completed 12.04.2021 | ||
| 500 | |a Date Revised 12.04.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2019 Elsevier B.V. All rights reserved. | ||
| 520 | |a INTRODUCTION: There is no standard procedure to evaluated the peak of reflex cough flow (PCF-reflex) in the literature, which is important assessment in subjects with acquired brain injury and tracheostomy cannula. The present study aims to investigate the PCF of the reflex cough in a broad sample of healthy controls and, furthermore, the presence and the strength of voluntary and reflex cough in subjects with ABI with tracheostomy cannula | ||
| 520 | |a MATERIALS AND METHODS: We recruited 147 participants including the healthy subjects (n = 105) and acquired brain injury subjects (n = 43), who underwent respiratory assessment: the Tidal Volume, Forced Vital Capacity, PCF of voluntary cough (PCF-voluntary) and PCF-reflex (using a spirometer connected with a nebulizer by a bidirectional) | ||
| 520 | |a RESULTS: The PCF-reflex of controls and subjects was significant lower than the PCF-voluntary (P < 0.01). The PCF-voluntary was not assessed in 26 (60.5 %) subjects due to severe cognitive deficit. In subjects without cognitive deficits (n = 17; 39.5 %), it was significantly lower than in healthy controls (p < 0.01). In contrast, the PCF-reflex was completed in all subjects and it was not significantly different from healthy controls. Furthermore, the strength of the PCF-reflex decreased with increasing inhalation numbers of nebulised air | ||
| 520 | |a CONCLUSION: Reflex cough behaviour differs largely from voluntary cough and the PCF results reflect this great discrepancy. PCF-reflex could be useful parameter for assessing the airway protection whereas PCF-voluntary for measuring airway clearance | ||
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Zanetti, Cristiano |e verfasserin |4 aut | |
| 700 | 1 | |a Gregorio, Caterina |e verfasserin |4 aut | |
| 700 | 1 | |a Koch, Isabella |e verfasserin |4 aut | |
| 700 | 1 | |a Vio, Agostino |e verfasserin |4 aut | |
| 700 | 1 | |a Palmer, Katie |e verfasserin |4 aut | |
| 700 | 1 | |a Meneghello, Francesca |e verfasserin |4 aut | |
| 700 | 1 | |a Piccione, Francesco |e verfasserin |4 aut | |
| 700 | 1 | |a Battel, Irene |e verfasserin |4 aut | |
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