Obesity-Hypoventilation Syndrome : Baseline Hemodynamic Status and Impact of non-Invasive Ventilation
Copyright © 2020 SEPAR. Publicado por Elsevier España, S.L.U. All rights reserved..
INTRODUCTION: Obesity-hypoventilation syndrome (OHS) is a risk factor for heart failure (HF). Some studies associate the use of non-invasive ventilation (NIV) with changes in hemodynamic parameters. Our objective was to describe the hemodynamic status of a group of patients with OHS and to study the effect of NIV.
PATIENTS AND METHODS: Patients with stable OHS treated with NIV were included in this cross-sectional repeated measurements study. Hemodynamics were measured by bioimpedance: 30minutes at baseline and another 30minutes on NIV. Cardiac output (CO), cardiac index, and systolic volume were measured. The CO calculated for each patient expressed as a percentage of the lower limit of normal (LLN) was taken as reference, and 2 groups were formed: patients without HF and normal CO (≥ 100% of LLN) and patients with HF and low CO (< 100% of LLN). The Mann-Whitney U test was used to compare independent variables and the Wilcoxon test was used for paired variables, with significance set at P<.05.
RESULTS: The final sample comprised 36 patients, aged 66 (± 8) years, 19 (52%) men. In 17 (46%) patients, HF was detected with a CO of 3.7 l/min (66%) compared to the group without HF, whose CO was 7 l/min (107%). After NIV, patients with HF showed improvement in CO (4.5 l/min (77%), P=.009, while the non-HF group remained unchanged, with CO 6.8 l/min (104%), P=.2.
CONCLUSION: A total of 46% of patients with stable OHS present HF; NIV improves hemodynamics and does not affect patients with normal CO.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:56 |
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| Enthalten in: |
Archivos de bronconeumologia - 56(2020), 7 vom: 12. Juli, Seite 441-445 |
| Sprache: |
Englisch |
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| Weiterer Titel: |
Síndrome de obesidad-hipoventilación: situación hemodinámica basal e impacto de la ventilación no invasiva |
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| Beteiligte Personen: |
Fernández Álvarez, Ramón [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 24.06.2021 Date Revised 24.06.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.arbres.2019.08.022 |
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| funding: |
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| PPN (Katalog-ID): |
NLM30482206X |
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| 100 | 1 | |a Fernández Álvarez, Ramón |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Obesity-Hypoventilation Syndrome |b Baseline Hemodynamic Status and Impact of non-Invasive Ventilation |
| 246 | 3 | 3 | |a Síndrome de obesidad-hipoventilación: situación hemodinámica basal e impacto de la ventilación no invasiva |
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| 500 | |a Date Completed 24.06.2021 | ||
| 500 | |a Date Revised 24.06.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2020 SEPAR. Publicado por Elsevier España, S.L.U. All rights reserved. | ||
| 520 | |a INTRODUCTION: Obesity-hypoventilation syndrome (OHS) is a risk factor for heart failure (HF). Some studies associate the use of non-invasive ventilation (NIV) with changes in hemodynamic parameters. Our objective was to describe the hemodynamic status of a group of patients with OHS and to study the effect of NIV | ||
| 520 | |a PATIENTS AND METHODS: Patients with stable OHS treated with NIV were included in this cross-sectional repeated measurements study. Hemodynamics were measured by bioimpedance: 30minutes at baseline and another 30minutes on NIV. Cardiac output (CO), cardiac index, and systolic volume were measured. The CO calculated for each patient expressed as a percentage of the lower limit of normal (LLN) was taken as reference, and 2 groups were formed: patients without HF and normal CO (≥ 100% of LLN) and patients with HF and low CO (< 100% of LLN). The Mann-Whitney U test was used to compare independent variables and the Wilcoxon test was used for paired variables, with significance set at P<.05 | ||
| 520 | |a RESULTS: The final sample comprised 36 patients, aged 66 (± 8) years, 19 (52%) men. In 17 (46%) patients, HF was detected with a CO of 3.7 l/min (66%) compared to the group without HF, whose CO was 7 l/min (107%). After NIV, patients with HF showed improvement in CO (4.5 l/min (77%), P=.009, while the non-HF group remained unchanged, with CO 6.8 l/min (104%), P=.2 | ||
| 520 | |a CONCLUSION: A total of 46% of patients with stable OHS present HF; NIV improves hemodynamics and does not affect patients with normal CO | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Cardiothoracic impedance | |
| 650 | 4 | |a Heart failure | |
| 650 | 4 | |a Impedancia cardiotorácica | |
| 650 | 4 | |a Insuficiencia cardiaca | |
| 650 | 4 | |a Non-invasive ventilation | |
| 650 | 4 | |a Obesity-hypoventilation syndrome | |
| 650 | 4 | |a Síndrome obesidad-hipoventilación | |
| 650 | 4 | |a Ventilación no invasiva | |
| 700 | 1 | |a Belda Ramirez, José |e verfasserin |4 aut | |
| 700 | 1 | |a Rubinos Cuadrado, Gemma |e verfasserin |4 aut | |
| 700 | 1 | |a Buchelli Ramirez, Herminia |e verfasserin |4 aut | |
| 700 | 1 | |a Fole Vazquez, David |e verfasserin |4 aut | |
| 700 | 1 | |a Iscar Urrutia, Marta |e verfasserin |4 aut | |
| 700 | 1 | |a Rodriguez Jerez, Francisco |e verfasserin |4 aut | |
| 700 | 1 | |a Vazquez Lopez, Maria Jose |e verfasserin |4 aut | |
| 700 | 1 | |a Casan Clara, Pere |e verfasserin |4 aut | |
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