Editorial Commentary : Is Medical Ozone Therapy Beneficial in the Treatment of Knee Osteoarthritis?
Copyright © 2019 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved..
Osteoarthritis is a degenerative joint disease that is difficult to manage and a major cause of disability in the elderly population. The use of ozone for treatment of knee osteoarthritis (KOA) is controversial and of interest. Although the exact mechanism of ozone for the treatment of KOA is not fully understood, it has been shown that ozone administration may promote oxidative preconditioning or adaptation to oxidative stress, which in turn will result in the stimulation of antioxidant endogenous system which prevents tissue damage. A number of European studies show ozone injection for treatment of KOA results in pain relief, disappearance of edema, and improved mobility. Dosages and volume of injections vary among studies, risk of bias is generally high, and outcomes are inconsistent and not uniformly excellent. At present, there is insufficient evidence to support the effectiveness of ozone therapy for KOA.
| Errataetall: |
CommentOn: Arthroscopy. 2020 Jan;36(1):277-286. - PMID 31679646 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:36 |
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| Enthalten in: |
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association - 36(2020), 1 vom: 15. Jan., Seite 287-288 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Manoto, Sello Lebohang [VerfasserIn] |
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Date Completed 03.04.2020 Date Revised 03.04.2020 published: Print CommentOn: Arthroscopy. 2020 Jan;36(1):277-286. - PMID 31679646 Citation Status MEDLINE |
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| doi: |
10.1016/j.arthro.2019.09.036 |
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NLM304650617 |
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2019 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved. | ||
| 520 | |a Osteoarthritis is a degenerative joint disease that is difficult to manage and a major cause of disability in the elderly population. The use of ozone for treatment of knee osteoarthritis (KOA) is controversial and of interest. Although the exact mechanism of ozone for the treatment of KOA is not fully understood, it has been shown that ozone administration may promote oxidative preconditioning or adaptation to oxidative stress, which in turn will result in the stimulation of antioxidant endogenous system which prevents tissue damage. A number of European studies show ozone injection for treatment of KOA results in pain relief, disappearance of edema, and improved mobility. Dosages and volume of injections vary among studies, risk of bias is generally high, and outcomes are inconsistent and not uniformly excellent. At present, there is insufficient evidence to support the effectiveness of ozone therapy for KOA | ||
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