The Association Between Keratoconus and Mitral Valve Prolapse : A Meta-Analysis
Copyright© Bentham Science Publishers; For any queries, please email at epubbenthamscience.net..
OBJECTIVE: The debate pertaining to the association between Keratoconus (KC) and Mitral Valve Prolapse (MVP) continues to occur among physicians. The results of cross-sectional studies attempting to present the co-existing prevalence of these two diseases remain indeterminate. We compiled the first meta-analysis to determine the pattern of prevalence between the two diseases.
METHODS: Two separate literature searches for cross-sectional studies were performed for this metaanalysis. The first search encompassed finding literature comparing the prevalence of KC between patients with MVP and a control group. The second search pertained to finding studies comparing the prevalence of MVP patients with KC and a control group.
RESULTS: Six studies reported the prevalence of MVP in patients with KC and a control group. The prevalence was 41.6% in patients with KC and 11.5% in patients without KC (OR = 7.06 [95% CI = 2.41-20.64]). There was a significant heterogeneity among the studies (I2 = 84%). Two studies showed the prevalence of KC in patients with MVP and a control group. The prevalence was 17.0% in patients with KC and 2.9% in the control group (OR = 5.07 [95% CI = 1.08-23.83]). There was no heterogeneity within the analysis (I2 = 0%).
CONCLUSION: There is a statistically significant co-existing prevalence between MVP and KC. Patients with KC are more likely to present with MVP, and patients with MVP are more likely to present with KC.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:16 |
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| Enthalten in: |
Current cardiology reviews - 16(2020), 2 vom: 02., Seite 147-152 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Siordia, Juan A [VerfasserIn] |
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| Links: |
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| Themen: |
Association |
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| Anmerkungen: |
Date Completed 27.07.2020 Date Revised 02.05.2021 published: Print Citation Status MEDLINE |
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| doi: |
10.2174/1573403X15666191129100928 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM303845287 |
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| 100 | 1 | |a Siordia, Juan A |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The Association Between Keratoconus and Mitral Valve Prolapse |b A Meta-Analysis |
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| 500 | |a Date Completed 27.07.2020 | ||
| 500 | |a Date Revised 02.05.2021 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright© Bentham Science Publishers; For any queries, please email at epubbenthamscience.net. | ||
| 520 | |a OBJECTIVE: The debate pertaining to the association between Keratoconus (KC) and Mitral Valve Prolapse (MVP) continues to occur among physicians. The results of cross-sectional studies attempting to present the co-existing prevalence of these two diseases remain indeterminate. We compiled the first meta-analysis to determine the pattern of prevalence between the two diseases | ||
| 520 | |a METHODS: Two separate literature searches for cross-sectional studies were performed for this metaanalysis. The first search encompassed finding literature comparing the prevalence of KC between patients with MVP and a control group. The second search pertained to finding studies comparing the prevalence of MVP patients with KC and a control group | ||
| 520 | |a RESULTS: Six studies reported the prevalence of MVP in patients with KC and a control group. The prevalence was 41.6% in patients with KC and 11.5% in patients without KC (OR = 7.06 [95% CI = 2.41-20.64]). There was a significant heterogeneity among the studies (I2 = 84%). Two studies showed the prevalence of KC in patients with MVP and a control group. The prevalence was 17.0% in patients with KC and 2.9% in the control group (OR = 5.07 [95% CI = 1.08-23.83]). There was no heterogeneity within the analysis (I2 = 0%) | ||
| 520 | |a CONCLUSION: There is a statistically significant co-existing prevalence between MVP and KC. Patients with KC are more likely to present with MVP, and patients with MVP are more likely to present with KC | ||
| 650 | 4 | |a Meta-Analysis | |
| 650 | 4 | |a Keratoconus | |
| 650 | 4 | |a association | |
| 650 | 4 | |a cardiology | |
| 650 | 4 | |a epidemiology | |
| 650 | 4 | |a mitral valve prolapse | |
| 650 | 4 | |a ophthalmology. | |
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