Tumor clinicopathological characteristics and their prognostic value in mucinous colorectal carcinoma
Aim: This study analyzed clinicopathological features of colorectal mucinous carcinoma and their prognostic values. Patients & method: This study enrolled 265 patients with mucinous colorectal cancer. Clinicopathological information and prognosis were reviewed retrospectively. Kaplan-Meier method, log- rank test and COX proportional hazard regression models were used. Results: In postoperative mucinous carcinoma patients (median age 56, 119 [44.9%] female), advanced tumor stage (odds ratio [OR]: 2.378; 95% CI: 1.512-3.741; p = 0.0002), poor differentiation (OR: 1.896; CI: 1.217-2.955; p = 0.0047) and right-sided tumors (OR: 2.421; CI: 1.145-5.102; p = 0.0206) were associated with shorter overall survival. Appendiceal/ileocecal cecal tumors were not different for prognosis. Conclusion: Mucinous colorectal carcinoma exhibits distinct tumor characteristics. Poor differentiation, advanced stage at presentation and the right side serve as negative prognostic factors.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2019 |
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| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:15 |
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| Enthalten in: |
Future oncology (London, England) - 15(2019), 35 vom: 11. Dez., Seite 4095-4104 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Luo, Cong [VerfasserIn] |
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| Links: |
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| Themen: |
Appendix |
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| Anmerkungen: |
Date Completed 10.04.2020 Date Revised 10.04.2020 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.2217/fon-2019-0342 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM303762454 |
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| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Aim: This study analyzed clinicopathological features of colorectal mucinous carcinoma and their prognostic values. Patients & method: This study enrolled 265 patients with mucinous colorectal cancer. Clinicopathological information and prognosis were reviewed retrospectively. Kaplan-Meier method, log- rank test and COX proportional hazard regression models were used. Results: In postoperative mucinous carcinoma patients (median age 56, 119 [44.9%] female), advanced tumor stage (odds ratio [OR]: 2.378; 95% CI: 1.512-3.741; p = 0.0002), poor differentiation (OR: 1.896; CI: 1.217-2.955; p = 0.0047) and right-sided tumors (OR: 2.421; CI: 1.145-5.102; p = 0.0206) were associated with shorter overall survival. Appendiceal/ileocecal cecal tumors were not different for prognosis. Conclusion: Mucinous colorectal carcinoma exhibits distinct tumor characteristics. Poor differentiation, advanced stage at presentation and the right side serve as negative prognostic factors | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a appendix | |
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| 650 | 4 | |a colorectal cancer | |
| 650 | 4 | |a mucinous adenocarcinoma | |
| 650 | 4 | |a pathology | |
| 650 | 4 | |a postoperative | |
| 650 | 4 | |a prognosis | |
| 650 | 4 | |a risk factors | |
| 650 | 4 | |a tumor characteristics | |
| 700 | 1 | |a Cen, Shuyi |e verfasserin |4 aut | |
| 700 | 1 | |a Ying, Jieer |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Xiaohong |e verfasserin |4 aut | |
| 700 | 1 | |a Fu, Zhixuan |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Peng |e verfasserin |4 aut | |
| 700 | 1 | |a Wu, Wei |e verfasserin |4 aut | |
| 700 | 1 | |a Ding, Guojun |e verfasserin |4 aut | |
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