A modular approach for cytosolic protein delivery : metal ion-induced self-assembly of gold nanoclusters as a general platform
We developed a versatile and modular method for cytosolic protein delivery through metal ion-induced co-assembly of gold nanoclusters and proteins into supramolecular assemblies. The versatility and high efficiency of this strategy to assemble and deliver various proteins into living cells were demonstrated. Importantly, the activity of proteins was maintained during the delivery. This modular approach provides an exciting and promising new nano-platform for cytosolic protein delivery.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2019 |
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| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:11 |
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| Enthalten in: |
Nanoscale - 11(2019), 46 vom: 28. Nov., Seite 22237-22242 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Wang, Lirui [VerfasserIn] |
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| Links: |
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| Themen: |
27432CM55Q |
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| Anmerkungen: |
Date Completed 15.04.2020 Date Revised 15.04.2020 published: Print Citation Status MEDLINE |
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| doi: |
10.1039/c9nr07334e |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM303440147 |
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a We developed a versatile and modular method for cytosolic protein delivery through metal ion-induced co-assembly of gold nanoclusters and proteins into supramolecular assemblies. The versatility and high efficiency of this strategy to assemble and deliver various proteins into living cells were demonstrated. Importantly, the activity of proteins was maintained during the delivery. This modular approach provides an exciting and promising new nano-platform for cytosolic protein delivery | ||
| 650 | 4 | |a Journal Article | |
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| 650 | 7 | |a Serum Albumin, Bovine |2 NLM | |
| 650 | 7 | |a 27432CM55Q |2 NLM | |
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| 700 | 1 | |a Zhang, Chunlei |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Tianliang |e verfasserin |4 aut | |
| 700 | 1 | |a Duan, Meng |e verfasserin |4 aut | |
| 700 | 1 | |a Xia, Fangfang |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Xinhong |e verfasserin |4 aut | |
| 700 | 1 | |a Song, Cunfeng |e verfasserin |4 aut | |
| 700 | 1 | |a Pan, Shaojun |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Bin |e verfasserin |4 aut | |
| 700 | 1 | |a Cui, Daxiang |e verfasserin |4 aut | |
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