Eribulin-induced Interstitial Pneumonia : A Case Series and Retrospective Cohort Study
Eribulin is a chemotherapeutic agent used for advanced breast cancer, but there are some reports of eribulin-induced lung injuries. Three of our patients experienced eribulin-related lung injuries. Radiology revealed organizing pneumonia in two cases and diffuse ground-glass shadows indicative of hypersensitivity pneumonitis in the third. A retrospective survey of patients treated with eribulin at our hospital identified no other cases of eribulin-induced lung injuries. Overall, drug-related lung injuries occurred in 2.8% of our eribulin-treated patients, which is similar to the rates reported for other anticancer drugs. The findings from these three cases provide guidance for the safe use of eribulin.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2020 |
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Erschienen: |
2020 |
Enthalten in: |
Zur Gesamtaufnahme - volume:59 |
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Enthalten in: |
Internal medicine (Tokyo, Japan) - 59(2020), 4 vom: 15. Feb., Seite 563-567 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Murakami, Manabu [VerfasserIn] |
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Links: |
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Themen: |
Antineoplastic Agents |
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Anmerkungen: |
Date Completed 02.09.2020 Date Revised 07.12.2022 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.2169/internalmedicine.2779-19 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM301952361 |
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520 | |a Eribulin is a chemotherapeutic agent used for advanced breast cancer, but there are some reports of eribulin-induced lung injuries. Three of our patients experienced eribulin-related lung injuries. Radiology revealed organizing pneumonia in two cases and diffuse ground-glass shadows indicative of hypersensitivity pneumonitis in the third. A retrospective survey of patients treated with eribulin at our hospital identified no other cases of eribulin-induced lung injuries. Overall, drug-related lung injuries occurred in 2.8% of our eribulin-treated patients, which is similar to the rates reported for other anticancer drugs. The findings from these three cases provide guidance for the safe use of eribulin | ||
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