Evaluation of neutrophil-lymphocyte ratio in predicting bloodstream infection
Aim: The prognostic role of neutrophil-to-lymphocyte ratio (NLR) in bloodstream infection (BSI) deserves further investigation. Patients & methods: The NLR values were measured and compared in BSI patients and healthy controls. The receiver operating characteristic of NLR and cut-off values were measured in BSI patients and subgroups. Results: We have measured the NLR of study group with 2160 BSI patients and normal group with 2523 healthy controls, which was significantly high in study group (11.36 ± 21.38 vs 2.53 ± 0.86; p < 0.001) and the area under the curve was 0.834 (95% CI: 0.825-0.842; p < 0.001). The critical value of NLR for diagnosis of BSI was 3.09, with a sensitivity of 75.3%, and a specificity of 93.6%. Conclusion: NLR is an effective diagnostic indicator of including BSIs of Gram-negative bacteria, Gram-positive bacteria and fungus.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2019 |
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| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:13 |
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| Enthalten in: |
Biomarkers in medicine - 13(2019), 15 vom: 18. Okt., Seite 1255-1261 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Qu, Jian [VerfasserIn] |
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| Links: |
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| Themen: |
Bloodstream infection |
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| Anmerkungen: |
Date Completed 06.07.2020 Date Revised 06.07.2020 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.2217/bmm-2018-0253 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM301874417 |
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| 500 | |a Date Completed 06.07.2020 | ||
| 500 | |a Date Revised 06.07.2020 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Aim: The prognostic role of neutrophil-to-lymphocyte ratio (NLR) in bloodstream infection (BSI) deserves further investigation. Patients & methods: The NLR values were measured and compared in BSI patients and healthy controls. The receiver operating characteristic of NLR and cut-off values were measured in BSI patients and subgroups. Results: We have measured the NLR of study group with 2160 BSI patients and normal group with 2523 healthy controls, which was significantly high in study group (11.36 ± 21.38 vs 2.53 ± 0.86; p < 0.001) and the area under the curve was 0.834 (95% CI: 0.825-0.842; p < 0.001). The critical value of NLR for diagnosis of BSI was 3.09, with a sensitivity of 75.3%, and a specificity of 93.6%. Conclusion: NLR is an effective diagnostic indicator of including BSIs of Gram-negative bacteria, Gram-positive bacteria and fungus | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a bloodstream infection | |
| 650 | 4 | |a neutrophil-to-lymphocyte ratio | |
| 650 | 4 | |a receiver operating characteristic curve | |
| 700 | 1 | |a Yuan, Hai-Yan |e verfasserin |4 aut | |
| 700 | 1 | |a Huang, Ying |e verfasserin |4 aut | |
| 700 | 1 | |a Qu, Qiang |e verfasserin |4 aut | |
| 700 | 1 | |a Ou-Yang, Zhan-Bo |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Guo-Hua |e verfasserin |4 aut | |
| 700 | 1 | |a Zhu, Hai-Hong |e verfasserin |4 aut | |
| 700 | 1 | |a Lu, Qiong |e verfasserin |4 aut | |
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