Multinodular and Vacuolating Posterior Fossa Lesions of Unknown Significance
© 2019 by American Journal of Neuroradiology..
Multinodular and vacuolating neuronal tumor of the cerebrum is a rare supratentorial brain tumor described for the first time in 2013. Here, we report 11 cases of infratentorial lesions showing similar striking imaging features consisting of a cluster of low T1-weighted imaging and high T2-FLAIR signal intensity nodules, which we referred to as multinodular and vacuolating posterior fossa lesions of unknown significance. No relationship was found between the location of the lesion and clinical symptoms. A T2-FLAIR hypointense central dot sign was present in images of 9/11 (82%) patients. Cortical involvement was present in 2/11 (18%) of patients. Only 1 nodule of 1 multinodular and vacuolating posterior fossa lesion of unknown significance showed enhancement on postcontrast T1WI. DWI, SWI, MRS, and PWI showed no malignant pattern. Lesions did not change in size or signal during a median follow-up of 3 years, suggesting that multinodular and vacuolating posterior fossa lesions of unknown significance are benign malformative lesions that do not require surgical intervention or removal.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2019 |
|---|---|
| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:40 |
|---|---|
| Enthalten in: |
AJNR. American journal of neuroradiology - 40(2019), 10 vom: 26. Okt., Seite 1689-1694 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Lecler, A [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
|---|
| Anmerkungen: |
Date Completed 22.06.2020 Date Revised 15.07.2020 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.3174/ajnr.A6223 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM301662061 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM301662061 | ||
| 003 | DE-627 | ||
| 005 | 20231225105108.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2019 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.3174/ajnr.A6223 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1005.xml |
| 035 | |a (DE-627)NLM301662061 | ||
| 035 | |a (NLM)31558497 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Lecler, A |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Multinodular and Vacuolating Posterior Fossa Lesions of Unknown Significance |
| 264 | 1 | |c 2019 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 22.06.2020 | ||
| 500 | |a Date Revised 15.07.2020 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2019 by American Journal of Neuroradiology. | ||
| 520 | |a Multinodular and vacuolating neuronal tumor of the cerebrum is a rare supratentorial brain tumor described for the first time in 2013. Here, we report 11 cases of infratentorial lesions showing similar striking imaging features consisting of a cluster of low T1-weighted imaging and high T2-FLAIR signal intensity nodules, which we referred to as multinodular and vacuolating posterior fossa lesions of unknown significance. No relationship was found between the location of the lesion and clinical symptoms. A T2-FLAIR hypointense central dot sign was present in images of 9/11 (82%) patients. Cortical involvement was present in 2/11 (18%) of patients. Only 1 nodule of 1 multinodular and vacuolating posterior fossa lesion of unknown significance showed enhancement on postcontrast T1WI. DWI, SWI, MRS, and PWI showed no malignant pattern. Lesions did not change in size or signal during a median follow-up of 3 years, suggesting that multinodular and vacuolating posterior fossa lesions of unknown significance are benign malformative lesions that do not require surgical intervention or removal | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Multicenter Study | |
| 700 | 1 | |a Bailleux, J |e verfasserin |4 aut | |
| 700 | 1 | |a Carsin, B |e verfasserin |4 aut | |
| 700 | 1 | |a Adle-Biassette, H |e verfasserin |4 aut | |
| 700 | 1 | |a Baloglu, S |e verfasserin |4 aut | |
| 700 | 1 | |a Bogey, C |e verfasserin |4 aut | |
| 700 | 1 | |a Bonneville, F |e verfasserin |4 aut | |
| 700 | 1 | |a Calvier, E |e verfasserin |4 aut | |
| 700 | 1 | |a Comby, P-O |e verfasserin |4 aut | |
| 700 | 1 | |a Cottier, J-P |e verfasserin |4 aut | |
| 700 | 1 | |a Cotton, F |e verfasserin |4 aut | |
| 700 | 1 | |a Deschamps, R |e verfasserin |4 aut | |
| 700 | 1 | |a Diard-Detoeuf, C |e verfasserin |4 aut | |
| 700 | 1 | |a Ducray, F |e verfasserin |4 aut | |
| 700 | 1 | |a Duron, L |e verfasserin |4 aut | |
| 700 | 1 | |a Drissi, C |e verfasserin |4 aut | |
| 700 | 1 | |a Elmaleh, M |e verfasserin |4 aut | |
| 700 | 1 | |a Farras, J |e verfasserin |4 aut | |
| 700 | 1 | |a Garcia, J A |e verfasserin |4 aut | |
| 700 | 1 | |a Gerardin, E |e verfasserin |4 aut | |
| 700 | 1 | |a Grand, S |e verfasserin |4 aut | |
| 700 | 1 | |a Jianu, D C |e verfasserin |4 aut | |
| 700 | 1 | |a Kremer, S |e verfasserin |4 aut | |
| 700 | 1 | |a Magne, N |e verfasserin |4 aut | |
| 700 | 1 | |a Mejdoubi, M |e verfasserin |4 aut | |
| 700 | 1 | |a Moulignier, A |e verfasserin |4 aut | |
| 700 | 1 | |a Ollivier, M |e verfasserin |4 aut | |
| 700 | 1 | |a Nagi, S |e verfasserin |4 aut | |
| 700 | 1 | |a Rodallec, M |e verfasserin |4 aut | |
| 700 | 1 | |a Sadik, J-C |e verfasserin |4 aut | |
| 700 | 1 | |a Shor, N |e verfasserin |4 aut | |
| 700 | 1 | |a Tourdias, T |e verfasserin |4 aut | |
| 700 | 1 | |a Vandendries, C |e verfasserin |4 aut | |
| 700 | 1 | |a Broquet, V |e verfasserin |4 aut | |
| 700 | 1 | |a Savatovsky, J |e verfasserin |4 aut | |
| 700 | 0 | |a ENIGMA Investigation Group (EuropeaN Interdisciplinary Group for MVNT Analysis) |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t AJNR. American journal of neuroradiology |d 1990 |g 40(2019), 10 vom: 26. Okt., Seite 1689-1694 |w (DE-627)NLM012664189 |x 1936-959X |7 nnns |
| 773 | 1 | 8 | |g volume:40 |g year:2019 |g number:10 |g day:26 |g month:10 |g pages:1689-1694 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.3174/ajnr.A6223 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 40 |j 2019 |e 10 |b 26 |c 10 |h 1689-1694 | ||