Case report : lenvatinib in neoadjuvant setting in a patient affected by invasive poorly differentiated thyroid carcinoma
We report a case of an elderly woman presenting with a huge cervical mass invading the tracheal lumen. Diagnosed as invasive poorly differentiated thyroid cancer, after an endotracheal biopsy, stenting and radiotherapy, it was judged eligible for total thyroidectomy, but surgery was delayed due to pulmonary thromboembolism. The patient was therefore treated with lenvatinib with a neoadjuvant intent until hemodynamic stability was obtained. Thyroidectomy and radioiodine therapy were then performed and the postdose scan revealed an area of modest uptake in the anterior part of the neck. The patient is now in a good clinical status and she continues her follow-up program without any adjuvant therapy.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2019 |
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| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:15 |
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| Enthalten in: |
Future oncology (London, England) - 15(2019), 24s vom: 06. Aug., Seite 13-19 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Gay, Stefano [VerfasserIn] |
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| Links: |
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| Themen: |
Case Reports |
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| Anmerkungen: |
Date Completed 31.01.2020 Date Revised 31.01.2020 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.2217/fon-2019-0099 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM299964043 |
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| 520 | |a We report a case of an elderly woman presenting with a huge cervical mass invading the tracheal lumen. Diagnosed as invasive poorly differentiated thyroid cancer, after an endotracheal biopsy, stenting and radiotherapy, it was judged eligible for total thyroidectomy, but surgery was delayed due to pulmonary thromboembolism. The patient was therefore treated with lenvatinib with a neoadjuvant intent until hemodynamic stability was obtained. Thyroidectomy and radioiodine therapy were then performed and the postdose scan revealed an area of modest uptake in the anterior part of the neck. The patient is now in a good clinical status and she continues her follow-up program without any adjuvant therapy | ||
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| 700 | 1 | |a Monti, Eleonora |e verfasserin |4 aut | |
| 700 | 1 | |a Trambaiolo Antonelli, Chiara |e verfasserin |4 aut | |
| 700 | 1 | |a Mora, Marco |e verfasserin |4 aut | |
| 700 | 1 | |a Spina, Bruno |e verfasserin |4 aut | |
| 700 | 1 | |a Ansaldo, Gianluca |e verfasserin |4 aut | |
| 700 | 1 | |a Teliti, Marsida |e verfasserin |4 aut | |
| 700 | 1 | |a Comina, Martina |e verfasserin |4 aut | |
| 700 | 1 | |a Conte, Lucia |e verfasserin |4 aut | |
| 700 | 1 | |a Minuto, Michele |e verfasserin |4 aut | |
| 700 | 1 | |a Varaldo, Elisabetta |e verfasserin |4 aut | |
| 700 | 1 | |a Zupo, Simonetta |e verfasserin |4 aut | |
| 700 | 1 | |a Massa, Barbara |e verfasserin |4 aut | |
| 700 | 1 | |a Morbelli, Silvia |e verfasserin |4 aut | |
| 700 | 1 | |a Giusti, Massimo |e verfasserin |4 aut | |
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