Tafenoquine : A 2018 Novel FDA-Approved Prodrug for the Radical Cure of Plasmodium vivax Malaria and Prophylaxis of Malaria
Tafenoquine (an 8-aminoquinoline) was approved by the Food and Drug Administration (FDA) in 2018 for the radical cure of Plasmodium vivax malaria and preventive action against malaria. Despite the fact that the mechanism of action of the drug remains unclear, all studies indicated that a metabolite is responsible for its efficacy. Routes for the preparation of the drug are described.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2019 |
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Erschienen: |
2019 |
Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
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Enthalten in: |
Pharmaceuticals (Basel, Switzerland) - 12(2019), 3 vom: 30. Juli |
Sprache: |
Englisch |
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Beteiligte Personen: |
Mayence, Annie [VerfasserIn] |
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Links: |
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Themen: |
Aminoquinoline |
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Anmerkungen: |
Date Revised 01.10.2020 published: Electronic Citation Status PubMed-not-MEDLINE |
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doi: |
10.3390/ph12030115 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM299775364 |
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