Recent advances of analogues of curcumin for treatment of cancer
Copyright © 2019 Elsevier Masson SAS. All rights reserved..
Curcumin (CU), an edible natural pigment from Curcuma Longa, has demonstrated extensive anti-tumor effect in vivo and in vitro. With the property of reversing drug resistance and low toxicity, CU has been considered to develop a new adjuvant chemotherapy protocol of cancer. However, the poor stability, solubility, in vivo bioavailability and weak activity of CU greatly limit its clinical application. Therefore, CU analogues have been extensively studied. Starting from the study of natural CU analogues, multiple approaches are being sought to obtain more stable, soluble and effective analogues of CU. This review focuses on the progress of these approaches to more potent CU analogues.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2019 |
|---|---|
| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:180 |
|---|---|
| Enthalten in: |
European journal of medicinal chemistry - 180(2019) vom: 15. Okt., Seite 524-535 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Zhao, Shijie [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Analogues |
|---|
| Anmerkungen: |
Date Completed 23.12.2019 Date Revised 23.12.2019 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.ejmech.2019.07.034 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM299484025 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM299484025 | ||
| 003 | DE-627 | ||
| 005 | 20231225100432.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2019 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.ejmech.2019.07.034 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n0998.xml |
| 035 | |a (DE-627)NLM299484025 | ||
| 035 | |a (NLM)31336310 | ||
| 035 | |a (PII)S0223-5234(19)30655-5 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Zhao, Shijie |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Recent advances of analogues of curcumin for treatment of cancer |
| 264 | 1 | |c 2019 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 23.12.2019 | ||
| 500 | |a Date Revised 23.12.2019 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2019 Elsevier Masson SAS. All rights reserved. | ||
| 520 | |a Curcumin (CU), an edible natural pigment from Curcuma Longa, has demonstrated extensive anti-tumor effect in vivo and in vitro. With the property of reversing drug resistance and low toxicity, CU has been considered to develop a new adjuvant chemotherapy protocol of cancer. However, the poor stability, solubility, in vivo bioavailability and weak activity of CU greatly limit its clinical application. Therefore, CU analogues have been extensively studied. Starting from the study of natural CU analogues, multiple approaches are being sought to obtain more stable, soluble and effective analogues of CU. This review focuses on the progress of these approaches to more potent CU analogues | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a Analogues | |
| 650 | 4 | |a Anticancer activity | |
| 650 | 4 | |a Curcumin | |
| 650 | 4 | |a Structural modification | |
| 650 | 7 | |a Antineoplastic Agents, Phytogenic |2 NLM | |
| 650 | 7 | |a Curcumin |2 NLM | |
| 650 | 7 | |a IT942ZTH98 |2 NLM | |
| 700 | 1 | |a Pi, Chao |e verfasserin |4 aut | |
| 700 | 1 | |a Ye, Yun |e verfasserin |4 aut | |
| 700 | 1 | |a Zhao, Ling |e verfasserin |4 aut | |
| 700 | 1 | |a Wei, Yumeng |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t European journal of medicinal chemistry |d 1994 |g 180(2019) vom: 15. Okt., Seite 524-535 |w (DE-627)NLM106608835 |x 1768-3254 |7 nnns |
| 773 | 1 | 8 | |g volume:180 |g year:2019 |g day:15 |g month:10 |g pages:524-535 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.ejmech.2019.07.034 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 180 |j 2019 |b 15 |c 10 |h 524-535 | ||