Our experience of repeat laparoscopic liver resection in patients with recurrent hepatocellular carcinoma
BACKGROUND: Repeat liver resection is an effective treatment approach for patients with recurrent hepatocellular cell carcinoma (HCC). However, the surgical feasibility and oncological significance of repeat laparoscopic liver resection (r-LLR) remain unproven. This study evaluates and compares the clinical outcomes of non-anatomic r-LLR applied towards recurrent HCC, with those of primary LLR (p-LLR) for primary HCC.
METHODS: This retrospective study reports 104 patients with HCC, treated with LLR between 2014 and 2018. Twenty eight of these patients underwent r-LLR for recurrent HCC. The clinical and surgical variables were reviewed for all cases.
RESULTS: The analysis was limited to non-anatomic resection across both groups (r-LLR: 89% (25/28) vs. p-LLR: 80% (61/76)). There were no statistically significant differences about patient background between the two groups, with the exception of Child-Pugh classification. r-LLR surgical techniques included single-site laparoscopic adhesiolysis (32%, 8/25), Pringle maneuver (8%, 2/25), and crush-clamp method using BiClamp for hepatic parenchymal transection (72%, 18/25). No severe postoperative complications were observed in the r-LLR group. Postoperative hospital stays and procedure-related postoperative survival were similar for both groups.
CONCLUSIONS: Non-anatomical r-LLR renders comparable surgical and oncological outcomes. Our data suggest that non-anatomical r-LLR is a safe and feasible therapeutic approach to recurrent HCC.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:34 |
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| Enthalten in: |
Surgical endoscopy - 34(2020), 5 vom: 01. Mai, Seite 2113-2119 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Ogawa, Hisataka [VerfasserIn] |
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| Links: |
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| Themen: |
Hepatocellular carcinoma |
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| Anmerkungen: |
Date Completed 28.05.2021 Date Revised 28.05.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1007/s00464-019-06992-8 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM299340031 |
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| 245 | 1 | 0 | |a Our experience of repeat laparoscopic liver resection in patients with recurrent hepatocellular carcinoma |
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: Repeat liver resection is an effective treatment approach for patients with recurrent hepatocellular cell carcinoma (HCC). However, the surgical feasibility and oncological significance of repeat laparoscopic liver resection (r-LLR) remain unproven. This study evaluates and compares the clinical outcomes of non-anatomic r-LLR applied towards recurrent HCC, with those of primary LLR (p-LLR) for primary HCC | ||
| 520 | |a METHODS: This retrospective study reports 104 patients with HCC, treated with LLR between 2014 and 2018. Twenty eight of these patients underwent r-LLR for recurrent HCC. The clinical and surgical variables were reviewed for all cases | ||
| 520 | |a RESULTS: The analysis was limited to non-anatomic resection across both groups (r-LLR: 89% (25/28) vs. p-LLR: 80% (61/76)). There were no statistically significant differences about patient background between the two groups, with the exception of Child-Pugh classification. r-LLR surgical techniques included single-site laparoscopic adhesiolysis (32%, 8/25), Pringle maneuver (8%, 2/25), and crush-clamp method using BiClamp for hepatic parenchymal transection (72%, 18/25). No severe postoperative complications were observed in the r-LLR group. Postoperative hospital stays and procedure-related postoperative survival were similar for both groups | ||
| 520 | |a CONCLUSIONS: Non-anatomical r-LLR renders comparable surgical and oncological outcomes. Our data suggest that non-anatomical r-LLR is a safe and feasible therapeutic approach to recurrent HCC | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Hepatocellular carcinoma | |
| 650 | 4 | |a Non-anatomical resection | |
| 650 | 4 | |a Repeat laparoscopic liver resection | |
| 700 | 1 | |a Nakahira, Shin |e verfasserin |4 aut | |
| 700 | 1 | |a Inoue, Masashi |e verfasserin |4 aut | |
| 700 | 1 | |a Irei, Toshimitsu |e verfasserin |4 aut | |
| 700 | 1 | |a Hasegawa, Makoto |e verfasserin |4 aut | |
| 700 | 1 | |a Kato, Kazuya |e verfasserin |4 aut | |
| 700 | 1 | |a Oyama, Keisuke |e verfasserin |4 aut | |
| 700 | 1 | |a Himura, Hoshi |e verfasserin |4 aut | |
| 700 | 1 | |a To, Takayuki |e verfasserin |4 aut | |
| 700 | 1 | |a Maki, Ryosuke |e verfasserin |4 aut | |
| 700 | 1 | |a Nishi, Hidemi |e verfasserin |4 aut | |
| 700 | 1 | |a Ohara, Nobuyoshi |e verfasserin |4 aut | |
| 700 | 1 | |a Mikami, Jota |e verfasserin |4 aut | |
| 700 | 1 | |a Makari, Yoichi |e verfasserin |4 aut | |
| 700 | 1 | |a Nakata, Ken |e verfasserin |4 aut | |
| 700 | 1 | |a Tsujie, Masaki |e verfasserin |4 aut | |
| 700 | 1 | |a Fujita, Junya |e verfasserin |4 aut | |
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