Thiazole in the targeted anticancer drug discovery
Cancer is known as one of the main causes of death in the world; and many compounds have been synthesized to date with potential use in cancer therapy. Thiazole is a versatile heterocycle, found in the structure of many drugs in use as well as anticancer agents. This review provides an overview of recent advances in thiazole-bearing compounds as anticancer agents with particular emphasis on their mechanism of action in cancerous cells. Chemical designs, structure-activity relationships and relevant preclinical properties have been comprehensively described.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2019 |
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Erschienen: |
2019 |
Enthalten in: |
Zur Gesamtaufnahme - volume:11 |
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Enthalten in: |
Future medicinal chemistry - 11(2019), 15 vom: 18. Aug., Seite 1929-1952 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Ayati, Adileh [VerfasserIn] |
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Links: |
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Anmerkungen: |
Date Completed 20.05.2020 Date Revised 20.05.2020 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.4155/fmc-2018-0416 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM299264629 |
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