The Effects of Hemocoagulase on Coagulation Factors in an Elderly Patient with Upper Gastrointestinal Hemorrhage : A Case Report

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BACKGROUND: Hemocoagulase agkistrodon has been widely used for visceral bleeding, however, its adverse reaction has not been fully recognized.

CASE REPORT: A 65-year-old female with upper gastrointestinal hemorrhage occurred severe coagulation disorder during her hospitalization. Transfusion of blood products can not improve coagulation function. Coagulation parameters returned to normal two days after discontinuation of hemocoagulase agkistrodon.

CONCLUSION: So intravenous administration of hemocoagulase should be cautiously used for the treatment of gastrointestinal bleeding.

Medienart:

E-Artikel

Erscheinungsjahr:

2019

Erschienen:

2019

Enthalten in:

Zur Gesamtaufnahme - volume:14

Enthalten in:

Current drug safety - 14(2019), 3 vom: 24., Seite 230-232

Sprache:

Englisch

Beteiligte Personen:

Zhang, Haiyan [VerfasserIn]

Links:

Volltext

Themen:

Batroxobin
Blood Coagulation Factors
Case Reports
Coagulationdisorder
EC 3.4.21.-
Enzymes
Fibrinopeptide
Gastrointestinal hemorrhage
Hemocoagulase agkistrodon
Hypofibrinogenemia.

Anmerkungen:

Date Completed 12.02.2020

Date Revised 12.02.2020

published: Print

Citation Status MEDLINE

doi:

10.2174/1574886314666190524093711

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM297426028