Digital image processing software for diagnosing diabetic retinopathy from fundus photograph

OBJECTIVE: The aim of this study was to develop automated software for screening and diagnosing diabetic retinopathy (DR) from fundus photograph of patients with diabetes mellitus.

METHODS: The extraction of clinically significant features to detect pathologies of DR and the severity classification were performed by using MATLAB R2015a with MATLAB Image Processing Toolbox. In addition, the graphic user interface was developed using the MATLAB GUI Toolbox. The accuracy of software was measured by comparing the obtained results to those of the diagnosis by the ophthalmologist.

RESULTS: A set of 400 fundus images, containing 21 normal fundus images and 379 DR fundus images (162 non-proliferative DR and 217 proliferative DR), was interpreted by the ophthalmologist as a reference standard. The initial result showed that the sensitivity, specificity and accuracy of this software in detection of DR were 98%, 67% and 96.25%, respectively. However, the accuracy of this software in classifying non-proliferative and proliferative diabetic retinopathy was 66.58%. The average time for processing is 7 seconds for one fundus image.

CONCLUSION: The automated DR screening software was developed by using MATLAB programming and yielded 96.25% accuracy for the detection of DR when compared to that of the diagnosis by the ophthalmologist. It may be a helpful tool for DR screening in the distant rural area where ophthalmologist is not available.

Medienart:

E-Artikel

Erscheinungsjahr:

2019

Erschienen:

2019

Enthalten in:

Zur Gesamtaufnahme - volume:13

Enthalten in:

Clinical ophthalmology (Auckland, N.Z.) - 13(2019) vom: 01., Seite 641-648

Sprache:

Englisch

Beteiligte Personen:

Ratanapakorn, Tanapat [VerfasserIn]
Daengphoonphol, Athiwath [VerfasserIn]
Eua-Anant, Nawapak [VerfasserIn]
Yospaiboon, Yosanan [VerfasserIn]

Links:

Volltext

Themen:

Automated diabetic retinopathy software
Diabetic retinopathy screening
Digital image processing
Fundus photography diagnosis
Journal Article

Anmerkungen:

Date Revised 08.04.2022

published: Electronic-eCollection

Citation Status PubMed-not-MEDLINE

doi:

10.2147/OPTH.S195617

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM297368028