Novel Orthobunyavirus Causing Severe Kidney Disease in Broiler Chickens, Malaysia, 2014-2017
During 2014-2017, we isolated a novel orthobunyavirus from broiler chickens with severe kidney lesions in the state of Kedah, Malaysia; we named the virus Kedah fatal kidney syndrome virus (KFKSV). Affected chickens became listless and diarrheic before dying suddenly. Necropsies detected pale and swollen kidneys with signs of gout, enlarged and fragile livers, and pale hearts. Experimental infection of broiler chickens with KFKSV reproduced the disease and pathologic conditions observed in the field, fulfilling the Koch's postulates. Gene sequencing indicated high nucleotide identities between KFKSV isolates (99%) and moderate nucleotide identities with the orthobunyavirus Umbre virus in the large (78%), medium (77%), and small (86%) genomic segments. KFKSV may be pathogenic for other host species, including humans.
| Errataetall: |
RetractionIn: Emerg Infect Dis. 2020 Aug;26(8):1964. - PMID 32679028 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2019 |
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| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:25 |
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| Enthalten in: |
Emerging infectious diseases - 25(2019), 6 vom: 01. Juni, Seite 1110-1117 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Palya, Vilmos [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 23.12.2019 Date Revised 04.02.2022 published: Print RetractionIn: Emerg Infect Dis. 2020 Aug;26(8):1964. - PMID 32679028 Citation Status MEDLINE |
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| doi: |
10.3201/eid2506.181661 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM297257021 |
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| 500 | |a Date Completed 23.12.2019 | ||
| 500 | |a Date Revised 04.02.2022 | ||
| 500 | |a published: Print | ||
| 500 | |a RetractionIn: Emerg Infect Dis. 2020 Aug;26(8):1964. - PMID 32679028 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a During 2014-2017, we isolated a novel orthobunyavirus from broiler chickens with severe kidney lesions in the state of Kedah, Malaysia; we named the virus Kedah fatal kidney syndrome virus (KFKSV). Affected chickens became listless and diarrheic before dying suddenly. Necropsies detected pale and swollen kidneys with signs of gout, enlarged and fragile livers, and pale hearts. Experimental infection of broiler chickens with KFKSV reproduced the disease and pathologic conditions observed in the field, fulfilling the Koch's postulates. Gene sequencing indicated high nucleotide identities between KFKSV isolates (99%) and moderate nucleotide identities with the orthobunyavirus Umbre virus in the large (78%), medium (77%), and small (86%) genomic segments. KFKSV may be pathogenic for other host species, including humans | ||
| 650 | 4 | |a Historical Article | |
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| 650 | 4 | |a Retracted Publication | |
| 650 | 4 | |a Kedah fatal kidney syndrome virus | |
| 650 | 4 | |a Malaysia | |
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| 650 | 4 | |a Peribunyaviridae | |
| 650 | 4 | |a Turlock serogroup | |
| 650 | 4 | |a broiler | |
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| 700 | 1 | |a Kovács, Edit Walkóné |e verfasserin |4 aut | |
| 700 | 1 | |a Marton, Szilvia |e verfasserin |4 aut | |
| 700 | 1 | |a Tatár-Kis, Tímea |e verfasserin |4 aut | |
| 700 | 1 | |a Felföldi, Balázs |e verfasserin |4 aut | |
| 700 | 1 | |a Forró, Barbara |e verfasserin |4 aut | |
| 700 | 1 | |a Domán, Marianna |e verfasserin |4 aut | |
| 700 | 1 | |a Bányai, Krisztián |e verfasserin |4 aut | |
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