Impact of moderate versus deep sedation on adenoma detection rate in index average-risk screening colonoscopies

Copyright © 2019 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved..

BACKGROUND AND AIMS: The debate between moderate sedation versus deep sedation for index average-risk screening colonoscopies is well known to gastroenterologists. Ensuring the best of all metrics to perform quality colonoscopies for colon cancer prevention is paramount for both patients and physicians alike, because colon cancer remains the leading cause of cancer death and is the most-used screening tool in the United States. The aim of this study was to determine if moderate sedation versus deep sedation affects outcomes of adenoma detection rate (ADR) or polyp detection rate (PDR) in index, average-risk colonoscopies for colon cancer screening.

METHODS: A retrospective, single, tertiary care outpatient center study of 585 healthy average-risk patients who underwent index screening colonoscopy between June 1, 2015 to December 31, 2015 (moderate sedation only) and June 1, 2016,to December 31, 2016 (deep sedation only) was performed after Institutional Review Board approval. Demographic data and polyp details were collected to determine ADR and PDR. Patients who were not average risk were excluded from the study.

RESULTS: A total of 585 index average-risk screening colonoscopies were included in this study with 57.7% moderate sedation and 42.2% deep sedation. Neither ADR nor PDR was significantly different between the 2 groups (44.1% vs 38.5% [P = .18] and 71.9% vs 67.6% [P = .27], respectively).

CONCLUSIONS: In index average-risk screening colonoscopies, deep sedation appears to have no benefit compared with moderate sedation for ADR and PDR.

Errataetall:

CommentIn: Gastrointest Endosc. 2020 Oct;92(4):985. - PMID 32964849

Medienart:

E-Artikel

Erscheinungsjahr:

2019

Erschienen:

2019

Enthalten in:

Zur Gesamtaufnahme - volume:90

Enthalten in:

Gastrointestinal endoscopy - 90(2019), 3 vom: 15. Sept., Seite 502-505

Sprache:

Englisch

Beteiligte Personen:

Turse, Erica P [VerfasserIn]
Dailey, Francis E [VerfasserIn]
Bechtold, Matthew L [VerfasserIn]

Links:

Volltext

Themen:

Comparative Study
Journal Article

Anmerkungen:

Date Completed 18.02.2020

Date Revised 17.02.2021

published: Print-Electronic

CommentIn: Gastrointest Endosc. 2020 Oct;92(4):985. - PMID 32964849

Citation Status MEDLINE

doi:

10.1016/j.gie.2019.05.011

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM297211927