Profiling older community-dwellers with hypovitaminosis D : A classification tree analysis

Despite the high prevalence of hypovitaminosis D in older adults, universal vitamin D supplementation is not recommended due to potential risk of intoxication. Our aim here was to determine the clinical profiles of older community-dwellers with hypovitaminosis D. The perspective is to build novel strategies to screen for and supplement those with hypovitaminosis D. A classification tree (CHAID analysis) was performed on multiple datasets standardizedly collected from 1991 older French community-dwelling volunteers ≥ 65 years in 2009-2012. Hypovitaminosis D was defined as serum 25-hydroxyvitamin D ≤ 50 nmol/L. CHAID analysis retained 5 clinical profiles of older community-dwellers with different risks of hypovitaminosis D up to 87.3%, based on various combinations of the following characteristics: polymorbidity, obesity, sadness and gait disorders. For instance, the probability of hypovitaminosis D was 1.42-fold higher [95CI: 1.27-1.59] for those with polymorbidity and gait disorders compared to those with no polymorbidity, no obesity and no sadness. In conclusion, these easily-recordable measures may be used in clinical routine to identify older community-dwellers for whom vitamin D supplementation should be initiated.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:90

Enthalten in:

International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition - 90(2020), 3-4 vom: 01. Juni, Seite 195-199

Sprache:

Englisch

Beteiligte Personen:

Chevallereau, Gaelle [VerfasserIn]
Legeay, Mathilde [VerfasserIn]
Duval, Guillaume T [VerfasserIn]
Karras, Spyridon N [VerfasserIn]
Fantino, Bruno [VerfasserIn]
Annweiler, Cedric [VerfasserIn]

Links:

Volltext

Themen:

1406-16-2
Classification tree
News
Older adults
Screening
Vitamin D
Vitamin D deficiency

Anmerkungen:

Date Completed 21.10.2020

Date Revised 21.10.2020

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1024/0300-9831/a000591

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM296755230