Revised Interpretation of the Hain Lifescience GenoType MTBC To Differentiate Mycobacterium canettii and Members of the Mycobacterium tuberculosis Complex
Using 894 phylogenetically diverse genomes of the Mycobacterium tuberculosis complex (MTBC), we simulated in silico the ability of the Hain Lifescience GenoType MTBC assay to differentiate the causative agents of tuberculosis. Here, we propose a revised interpretation of this assay to reflect its strengths (e.g., it can distinguish some strains of Mycobacterium canettii and variants of Mycobacterium bovis that are not intrinsically resistant to pyrazinamide) and limitations (e.g., Mycobacterium orygis cannot be differentiated from Mycobacterium africanum).
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2019 |
|---|---|
| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:63 |
|---|---|
| Enthalten in: |
Antimicrobial agents and chemotherapy - 63(2019), 6 vom: 08. Juni |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Loiseau, Chloé [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Genotyping |
|---|
| Anmerkungen: |
Date Completed 30.04.2020 Date Revised 16.07.2022 published: Electronic-Print Citation Status MEDLINE |
|---|
| doi: |
10.1128/AAC.00159-19 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM295838388 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM295838388 | ||
| 003 | DE-627 | ||
| 005 | 20231225084531.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2019 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1128/AAC.00159-19 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n0986.xml |
| 035 | |a (DE-627)NLM295838388 | ||
| 035 | |a (NLM)30962348 | ||
| 035 | |a (PII)e00159-19 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Loiseau, Chloé |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Revised Interpretation of the Hain Lifescience GenoType MTBC To Differentiate Mycobacterium canettii and Members of the Mycobacterium tuberculosis Complex |
| 264 | 1 | |c 2019 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 30.04.2020 | ||
| 500 | |a Date Revised 16.07.2022 | ||
| 500 | |a published: Electronic-Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Using 894 phylogenetically diverse genomes of the Mycobacterium tuberculosis complex (MTBC), we simulated in silico the ability of the Hain Lifescience GenoType MTBC assay to differentiate the causative agents of tuberculosis. Here, we propose a revised interpretation of this assay to reflect its strengths (e.g., it can distinguish some strains of Mycobacterium canettii and variants of Mycobacterium bovis that are not intrinsically resistant to pyrazinamide) and limitations (e.g., Mycobacterium orygis cannot be differentiated from Mycobacterium africanum) | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Mycobacterium tuberculosis | |
| 650 | 4 | |a genotyping | |
| 650 | 4 | |a intrinsic antibiotic resistance | |
| 700 | 1 | |a Brites, Daniela |e verfasserin |4 aut | |
| 700 | 1 | |a Moser, Irmgard |e verfasserin |4 aut | |
| 700 | 1 | |a Coll, Francesc |e verfasserin |4 aut | |
| 700 | 1 | |a Pourcel, Christine |e verfasserin |4 aut | |
| 700 | 1 | |a Robbe-Austerman, Suelee |e verfasserin |4 aut | |
| 700 | 1 | |a Escuyer, Vincent |e verfasserin |4 aut | |
| 700 | 1 | |a Musser, Kimberlee A |e verfasserin |4 aut | |
| 700 | 1 | |a Peacock, Sharon J |e verfasserin |4 aut | |
| 700 | 1 | |a Feuerriegel, Silke |e verfasserin |4 aut | |
| 700 | 1 | |a Kohl, Thomas A |e verfasserin |4 aut | |
| 700 | 1 | |a Niemann, Stefan |e verfasserin |4 aut | |
| 700 | 1 | |a Gagneux, Sebastien |e verfasserin |4 aut | |
| 700 | 1 | |a Köser, Claudio U |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Antimicrobial agents and chemotherapy |d 1972 |g 63(2019), 6 vom: 08. Juni |w (DE-627)NLM000026506 |x 1098-6596 |7 nnns |
| 773 | 1 | 8 | |g volume:63 |g year:2019 |g number:6 |g day:08 |g month:06 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1128/AAC.00159-19 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 63 |j 2019 |e 6 |b 08 |c 06 | ||