Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk
The aim of the study was to evaluate sleep duration and sleep variability in relation to serum uric acid (SUA) concentrations and SUA to creatinine ratio. This is a cross-sectional analysis of baseline data from 1842 elderly participants with overweight/obesity and metabolic syndromein the (Prevención con Dieta Mediterránea) PREDIMED-Plus trial. Accelerometry-derived sleep duration and sleep variability were measured. Linear regression models were fitted to examine the aforementioned associations. A 1 hour/night increment in sleep duration was inversely associated with SUA concentrations (β = 0.07, p = 0.047). Further adjustment for leukocytes attenuated this association (p = 0.050). Each 1-hour increment in sleep duration was inversely associated with SUA to creatinine ratio (β = 0.15, p = 0.001). The findings of this study suggest that longer sleep duration is associated with lower SUA concentrations and lower SUA to creatinine ratio.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2019 |
---|---|
Erschienen: |
2019 |
Enthalten in: |
Zur Gesamtaufnahme - volume:11 |
---|---|
Enthalten in: |
Nutrients - 11(2019), 4 vom: 01. Apr. |
Sprache: |
Englisch |
---|
Links: |
---|
Themen: |
268B43MJ25 |
---|
Anmerkungen: |
Date Completed 27.08.2019 Date Revised 25.02.2020 published: Electronic Citation Status MEDLINE |
---|
doi: |
10.3390/nu11040761 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM295616113 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM295616113 | ||
003 | DE-627 | ||
005 | 20231225084041.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231225s2019 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.3390/nu11040761 |2 doi | |
028 | 5 | 2 | |a pubmed24n0985.xml |
035 | |a (DE-627)NLM295616113 | ||
035 | |a (NLM)30939748 | ||
035 | |a (PII)E761 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Papandreou, Christopher |e verfasserin |4 aut | |
245 | 1 | 0 | |a Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk |
264 | 1 | |c 2019 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Completed 27.08.2019 | ||
500 | |a Date Revised 25.02.2020 | ||
500 | |a published: Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a The aim of the study was to evaluate sleep duration and sleep variability in relation to serum uric acid (SUA) concentrations and SUA to creatinine ratio. This is a cross-sectional analysis of baseline data from 1842 elderly participants with overweight/obesity and metabolic syndromein the (Prevención con Dieta Mediterránea) PREDIMED-Plus trial. Accelerometry-derived sleep duration and sleep variability were measured. Linear regression models were fitted to examine the aforementioned associations. A 1 hour/night increment in sleep duration was inversely associated with SUA concentrations (β = 0.07, p = 0.047). Further adjustment for leukocytes attenuated this association (p = 0.050). Each 1-hour increment in sleep duration was inversely associated with SUA to creatinine ratio (β = 0.15, p = 0.001). The findings of this study suggest that longer sleep duration is associated with lower SUA concentrations and lower SUA to creatinine ratio | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Multicenter Study | |
650 | 4 | |a actigraphy | |
650 | 4 | |a serum uric acid | |
650 | 4 | |a serum uric acid to creatinine ratio | |
650 | 4 | |a sleep duration | |
650 | 7 | |a Biomarkers |2 NLM | |
650 | 7 | |a Uric Acid |2 NLM | |
650 | 7 | |a 268B43MJ25 |2 NLM | |
650 | 7 | |a Creatinine |2 NLM | |
650 | 7 | |a AYI8EX34EU |2 NLM | |
700 | 1 | |a Babio, Nancy |e verfasserin |4 aut | |
700 | 1 | |a Díaz-López, Andrés |e verfasserin |4 aut | |
700 | 1 | |a Martínez-González, Miguel Á |e verfasserin |4 aut | |
700 | 1 | |a Becerra-Tomas, Nerea |e verfasserin |4 aut | |
700 | 1 | |a Corella, Dolores |e verfasserin |4 aut | |
700 | 1 | |a Schröder, Helmut |e verfasserin |4 aut | |
700 | 1 | |a Romaguera, Dora |e verfasserin |4 aut | |
700 | 1 | |a Vioque, Jesús |e verfasserin |4 aut | |
700 | 1 | |a Alonso-Gómez, Ángel M |e verfasserin |4 aut | |
700 | 1 | |a Wärnberg, Julia |e verfasserin |4 aut | |
700 | 1 | |a Martínez, Alfredo J |e verfasserin |4 aut | |
700 | 1 | |a Serra-Majem, Lluís |e verfasserin |4 aut | |
700 | 1 | |a Estruch, Ramon |e verfasserin |4 aut | |
700 | 1 | |a Muñoz-Garach, Araceli |e verfasserin |4 aut | |
700 | 1 | |a Lapetra, José |e verfasserin |4 aut | |
700 | 1 | |a Pintó, Xavier |e verfasserin |4 aut | |
700 | 1 | |a Tur, Josep A |e verfasserin |4 aut | |
700 | 1 | |a Garcia-Rios, Antonio |e verfasserin |4 aut | |
700 | 1 | |a Bueno-Cavanillas, Aurora |e verfasserin |4 aut | |
700 | 1 | |a Delgado-Rodríguez, Miguel |e verfasserin |4 aut | |
700 | 1 | |a Matía-Martín, Pilar |e verfasserin |4 aut | |
700 | 1 | |a Daimiel, Lidia |e verfasserin |4 aut | |
700 | 1 | |a M Sánchez, Vicente |e verfasserin |4 aut | |
700 | 1 | |a Vidal, Josep |e verfasserin |4 aut | |
700 | 1 | |a Vázquez, Clotilde |e verfasserin |4 aut | |
700 | 1 | |a Ros, Emilio |e verfasserin |4 aut | |
700 | 1 | |a Ruiz-Canela, Miguel |e verfasserin |4 aut | |
700 | 1 | |a Bulló, Mónica |e verfasserin |4 aut | |
700 | 1 | |a Sorli, Jose V |e verfasserin |4 aut | |
700 | 1 | |a Quifer, Mireia |e verfasserin |4 aut | |
700 | 1 | |a Colom, Antoni |e verfasserin |4 aut | |
700 | 1 | |a Oncina-Canovas, Alejandro |e verfasserin |4 aut | |
700 | 1 | |a T Sierra, Lucas |e verfasserin |4 aut | |
700 | 1 | |a Barón-López, Javier |e verfasserin |4 aut | |
700 | 1 | |a Pérez-Farinós, Napoleón |e verfasserin |4 aut | |
700 | 1 | |a Abete, Itziar |e verfasserin |4 aut | |
700 | 1 | |a Sanchez-Villegas, Almudena |e verfasserin |4 aut | |
700 | 1 | |a Casas, Rosa |e verfasserin |4 aut | |
700 | 1 | |a F García, José C |e verfasserin |4 aut | |
700 | 1 | |a Santos-Lozano, José M |e verfasserin |4 aut | |
700 | 1 | |a Corbella, Emili |e verfasserin |4 aut | |
700 | 1 | |a Del M Bibiloni, Maria |e verfasserin |4 aut | |
700 | 1 | |a Diez-Espino, Javier |e verfasserin |4 aut | |
700 | 1 | |a Asensio, Eva M |e verfasserin |4 aut | |
700 | 1 | |a Torras, Laura |e verfasserin |4 aut | |
700 | 1 | |a Morey, Marga |e verfasserin |4 aut | |
700 | 1 | |a Compañ-Gabucio, Laura |e verfasserin |4 aut | |
700 | 1 | |a S Lete, Itziar |e verfasserin |4 aut | |
700 | 1 | |a Cenoz-Osinaga, Juan C |e verfasserin |4 aut | |
700 | 1 | |a Castañer, Olga |e verfasserin |4 aut | |
700 | 1 | |a Salas-Salvadó, Jordi |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Nutrients |d 2009 |g 11(2019), 4 vom: 01. Apr. |w (DE-627)NLM206140738 |x 2072-6643 |7 nnns |
773 | 1 | 8 | |g volume:11 |g year:2019 |g number:4 |g day:01 |g month:04 |
856 | 4 | 0 | |u http://dx.doi.org/10.3390/nu11040761 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 11 |j 2019 |e 4 |b 01 |c 04 |