Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk

The aim of the study was to evaluate sleep duration and sleep variability in relation to serum uric acid (SUA) concentrations and SUA to creatinine ratio. This is a cross-sectional analysis of baseline data from 1842 elderly participants with overweight/obesity and metabolic syndromein the (Prevención con Dieta Mediterránea) PREDIMED-Plus trial. Accelerometry-derived sleep duration and sleep variability were measured. Linear regression models were fitted to examine the aforementioned associations. A 1 hour/night increment in sleep duration was inversely associated with SUA concentrations (β = 0.07, p = 0.047). Further adjustment for leukocytes attenuated this association (p = 0.050). Each 1-hour increment in sleep duration was inversely associated with SUA to creatinine ratio (β = 0.15, p = 0.001). The findings of this study suggest that longer sleep duration is associated with lower SUA concentrations and lower SUA to creatinine ratio.

Medienart:

E-Artikel

Erscheinungsjahr:

2019

Erschienen:

2019

Enthalten in:

Zur Gesamtaufnahme - volume:11

Enthalten in:

Nutrients - 11(2019), 4 vom: 01. Apr.

Sprache:

Englisch

Beteiligte Personen:

Papandreou, Christopher [VerfasserIn]
Babio, Nancy [VerfasserIn]
Díaz-López, Andrés [VerfasserIn]
Martínez-González, Miguel Á [VerfasserIn]
Becerra-Tomas, Nerea [VerfasserIn]
Corella, Dolores [VerfasserIn]
Schröder, Helmut [VerfasserIn]
Romaguera, Dora [VerfasserIn]
Vioque, Jesús [VerfasserIn]
Alonso-Gómez, Ángel M [VerfasserIn]
Wärnberg, Julia [VerfasserIn]
Martínez, Alfredo J [VerfasserIn]
Serra-Majem, Lluís [VerfasserIn]
Estruch, Ramon [VerfasserIn]
Muñoz-Garach, Araceli [VerfasserIn]
Lapetra, José [VerfasserIn]
Pintó, Xavier [VerfasserIn]
Tur, Josep A [VerfasserIn]
Garcia-Rios, Antonio [VerfasserIn]
Bueno-Cavanillas, Aurora [VerfasserIn]
Delgado-Rodríguez, Miguel [VerfasserIn]
Matía-Martín, Pilar [VerfasserIn]
Daimiel, Lidia [VerfasserIn]
M Sánchez, Vicente [VerfasserIn]
Vidal, Josep [VerfasserIn]
Vázquez, Clotilde [VerfasserIn]
Ros, Emilio [VerfasserIn]
Ruiz-Canela, Miguel [VerfasserIn]
Bulló, Mónica [VerfasserIn]
Sorli, Jose V [VerfasserIn]
Quifer, Mireia [VerfasserIn]
Colom, Antoni [VerfasserIn]
Oncina-Canovas, Alejandro [VerfasserIn]
T Sierra, Lucas [VerfasserIn]
Barón-López, Javier [VerfasserIn]
Pérez-Farinós, Napoleón [VerfasserIn]
Abete, Itziar [VerfasserIn]
Sanchez-Villegas, Almudena [VerfasserIn]
Casas, Rosa [VerfasserIn]
F García, José C [VerfasserIn]
Santos-Lozano, José M [VerfasserIn]
Corbella, Emili [VerfasserIn]
Del M Bibiloni, Maria [VerfasserIn]
Diez-Espino, Javier [VerfasserIn]
Asensio, Eva M [VerfasserIn]
Torras, Laura [VerfasserIn]
Morey, Marga [VerfasserIn]
Compañ-Gabucio, Laura [VerfasserIn]
S Lete, Itziar [VerfasserIn]
Cenoz-Osinaga, Juan C [VerfasserIn]
Castañer, Olga [VerfasserIn]
Salas-Salvadó, Jordi [VerfasserIn]

Links:

Volltext

Themen:

268B43MJ25
AYI8EX34EU
Actigraphy
Biomarkers
Creatinine
Journal Article
Multicenter Study
Serum uric acid
Serum uric acid to creatinine ratio
Sleep duration
Uric Acid

Anmerkungen:

Date Completed 27.08.2019

Date Revised 25.02.2020

published: Electronic

Citation Status MEDLINE

doi:

10.3390/nu11040761

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM295616113