Progress in Molecularly Imprinted Polymers for Biomedical Applications

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BACKGROUND: Molecularly Imprinted Polymers (MIPs), a type of biomimetic materials have attracted considerable interest owing to their cost-effectiveness, good physiochemical stability, favorable specificity and selectivity for target analytes, and long shelf life. These materials are able to mimic natural recognition entities, including biological receptors and antibodies, providing a versatile platform to achieve the desirable functionality for various biomedical applications.

OBJECTIVE: In this review article, we introduce the most recent development of MIPs to date. We first highlight the advantages of using MIPs for a broad range of biomedical applications. We then review their various methods of synthesis along with their latest progress in biomedical applications, including biosensing, drug delivery, cell imaging and drug discovery. Lastly, the existing challenges and future perspectives of MIPs for biomedical applications are briefly discussed.

CONCLUSION: We envision that MIPs may be used as potential materials for diverse biomedical applications in the near future.

Medienart:

E-Artikel

Erscheinungsjahr:

2019

Erschienen:

2019

Enthalten in:

Zur Gesamtaufnahme - volume:22

Enthalten in:

Combinatorial chemistry & high throughput screening - 22(2019), 2 vom: 27., Seite 78-88

Sprache:

Englisch

Beteiligte Personen:

Choi, Jane Ru [VerfasserIn]
Yong, Kar Wey [VerfasserIn]
Choi, Jean Yu [VerfasserIn]
Cowie, Alistair C [VerfasserIn]

Links:

Volltext

Themen:

Antibodies
Biomedical applications
Biosensing
Cell imaging
Drug delivery
Drugdiscovery.
Journal Article
Molecularly imprinted polymers
Polymers
Research Support, Non-U.S. Gov't
Review

Anmerkungen:

Date Completed 14.02.2020

Date Revised 14.02.2020

published: Print

Citation Status MEDLINE

doi:

10.2174/1386207322666190325115526

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM295363398