The effect of LILRB1 but not LILRA3 gene polymorphism in immunopathology of ankylosing spondylitis-A parallel to KIR genes

© 2019 John Wiley & Sons Ltd..

LILR and KIR receptors recognize HLA-B27 and may influence immune response in ankylosing spondylitis (AS) development. Purpose of the study was to analyse LILRB1/LILRA3 polymorphisms in AS. We observed a possible protective effect of the T allele of LILRB1 rs1061680:T>C and no association with insertion/deletion polymorphisms of LILRA3 with AS.

Medienart:

E-Artikel

Erscheinungsjahr:

2019

Erschienen:

2019

Enthalten in:

Zur Gesamtaufnahme - volume:46

Enthalten in:

International journal of immunogenetics - 46(2019), 3 vom: 06. Juni, Seite 146-151

Sprache:

Englisch

Beteiligte Personen:

Majorczyk, Edyta [VerfasserIn]
Wiśniewski, Andrzej [VerfasserIn]
Zoń-Giebel, Aleksandra [VerfasserIn]
Chlebicki, Arkadiusz [VerfasserIn]
Wiland, Piotr [VerfasserIn]
Kuśnierczyk, Piotr [VerfasserIn]

Links:

Volltext

Themen:

Ankylosing spondylitis
Antigens, CD
Genetics
HLA-B27
Journal Article
KIR
LILR
LILRA3 protein, human
LILRB1 protein, human
Leukocyte Immunoglobulin-like Receptor B1
Receptors, Immunologic
Receptors, KIR

Anmerkungen:

Date Completed 07.10.2019

Date Revised 17.12.2019

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1111/iji.12422

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM29515599X