Herpes simplex virus keratouveitis recurrence following intravitreal bevacizumab injection
We report a case of recurrence of herpes simplex virus (HSV) keratouveitis following the intravitreal injection of bevacizumab for macular edema secondary to central retinal vein occlusion (CRVO) in a previously adequately treated patient of herpetic keratouveitis. A 47-year-old man with the previous history of HSV keratouveitis was administered 2 doses of intravitreal bevacizumab in the right eye for CRVO, at an interval of 4 weeks. Following the second dose, the patient developed decreased vision, corneal edema, and anterior segment inflammation. Since he was a previously known case of HSV keratouveitis with a positive polymerase chain reaction for HSV from the aqueous, oral valacyclovir was started along with topical steroids and cycloplegics. He showed a good response to treatment with resolution of keratouveitis. This case demonstrates that the recurrence of herpetic keratouveitis can be a possible complication of intravitreal bevacizumab, which may occur even after prior uneventful injections.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2019 |
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| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
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| Enthalten in: |
Oman journal of ophthalmology - 12(2019), 1 vom: 20. Jan., Seite 53-54 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Sharma, Ashok [VerfasserIn] |
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| Links: |
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| Themen: |
Bevacizumab |
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| Anmerkungen: |
Date Revised 29.09.2020 published: Print Citation Status PubMed-not-MEDLINE |
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| doi: |
10.4103/ojo.OJO_147_2016 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM294126627 |
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| 245 | 1 | 0 | |a Herpes simplex virus keratouveitis recurrence following intravitreal bevacizumab injection |
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| 500 | |a published: Print | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a We report a case of recurrence of herpes simplex virus (HSV) keratouveitis following the intravitreal injection of bevacizumab for macular edema secondary to central retinal vein occlusion (CRVO) in a previously adequately treated patient of herpetic keratouveitis. A 47-year-old man with the previous history of HSV keratouveitis was administered 2 doses of intravitreal bevacizumab in the right eye for CRVO, at an interval of 4 weeks. Following the second dose, the patient developed decreased vision, corneal edema, and anterior segment inflammation. Since he was a previously known case of HSV keratouveitis with a positive polymerase chain reaction for HSV from the aqueous, oral valacyclovir was started along with topical steroids and cycloplegics. He showed a good response to treatment with resolution of keratouveitis. This case demonstrates that the recurrence of herpetic keratouveitis can be a possible complication of intravitreal bevacizumab, which may occur even after prior uneventful injections | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Bevacizumab | |
| 650 | 4 | |a central retinal vein occlusion | |
| 650 | 4 | |a herpes simplex virus | |
| 650 | 4 | |a keratouveitis | |
| 650 | 4 | |a recurrence | |
| 700 | 1 | |a Singh, Simar Rajan |e verfasserin |4 aut | |
| 700 | 1 | |a Dogra, Mohit |e verfasserin |4 aut | |
| 700 | 1 | |a Singh, Chintan |e verfasserin |4 aut | |
| 700 | 1 | |a Singh, Ramandeep |e verfasserin |4 aut | |
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