Pulmonary histiocytosis : beyond Langerhans cell histiocytosis related to smoking
Copyright © 2019 SERAM. Publicado por Elsevier España, S.L.U. All rights reserved..
OBJECTIVE: To review the imaging findings for the different types of pulmonary histiocytosis. In particular, in addition to the well-known pulmonary Langerhans cell histiocytosis related to smoking and its possible appearance in nonsmokers, we focus on non-Langerhans cell histiocytosis in Rosai-Dorfman disease and Erdheim-Chester disease. We also review the etiopathogenesis, histology, clinical presentation, and treatment of pulmonary histiocytosis.
CONCLUSION: Langerhans cell histiocytosis, Rosai-Dorfman disease, and Erdheim-Chester disease are idiopathic diseases in which the proliferation and infiltration of histiocytes is the histologic finding that confirms the diagnosis. Langerhans cell histiocytosis manifests as nodules and cysts that spare the costophrenic angles; it typically appears in smokers. Although it is uncommon in nonsmokers, Langerhans cell histiocytosis should also be considered in nonsmokers treated with chemotherapy and radiotherapy in whom cavitated nodules appear and should be included in the differential diagnosis together with metastatic disease and opportunistic infections. Rosai-Dorfman disease and Erdheim-Chester disease present with less specific thoracic findings such as adenopathies, interstitial thickening, and pleural effusion. In Erdheim-Chester disease, the characteristic extrathoracic manifestations are usually key for the diagnosis.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2019 |
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| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:61 |
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| Enthalten in: |
Radiologia - 61(2019), 3 vom: 01. Mai, Seite 215-224 |
| Sprache: |
Englisch |
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| Weiterer Titel: |
Histiocitosis pulmonar: más allá de la histiocitosis de células de Langerhans relacionada con el tabaco |
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| Beteiligte Personen: |
Gallego, C Trejo [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 16.12.2019 Date Revised 27.05.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.rx.2018.11.003 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM293138060 |
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| 520 | |a Copyright © 2019 SERAM. Publicado por Elsevier España, S.L.U. All rights reserved. | ||
| 520 | |a OBJECTIVE: To review the imaging findings for the different types of pulmonary histiocytosis. In particular, in addition to the well-known pulmonary Langerhans cell histiocytosis related to smoking and its possible appearance in nonsmokers, we focus on non-Langerhans cell histiocytosis in Rosai-Dorfman disease and Erdheim-Chester disease. We also review the etiopathogenesis, histology, clinical presentation, and treatment of pulmonary histiocytosis | ||
| 520 | |a CONCLUSION: Langerhans cell histiocytosis, Rosai-Dorfman disease, and Erdheim-Chester disease are idiopathic diseases in which the proliferation and infiltration of histiocytes is the histologic finding that confirms the diagnosis. Langerhans cell histiocytosis manifests as nodules and cysts that spare the costophrenic angles; it typically appears in smokers. Although it is uncommon in nonsmokers, Langerhans cell histiocytosis should also be considered in nonsmokers treated with chemotherapy and radiotherapy in whom cavitated nodules appear and should be included in the differential diagnosis together with metastatic disease and opportunistic infections. Rosai-Dorfman disease and Erdheim-Chester disease present with less specific thoracic findings such as adenopathies, interstitial thickening, and pleural effusion. In Erdheim-Chester disease, the characteristic extrathoracic manifestations are usually key for the diagnosis | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Computed tomography | |
| 650 | 4 | |a Enfermedad de Erdheim Chester | |
| 650 | 4 | |a Erdheim-Chester disease | |
| 650 | 4 | |a Histiocitosis de células de Langerhans | |
| 650 | 4 | |a Histiocitosis sinusal | |
| 650 | 4 | |a Langerhans cells histiocytosis | |
| 650 | 4 | |a Sinus histiocytosis | |
| 650 | 4 | |a Tomografía computarizada | |
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| 700 | 1 | |a Mancheño, N |e verfasserin |4 aut | |
| 700 | 1 | |a Flors, L |e verfasserin |4 aut | |
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