Impact of health care-associated community-onset cellulitis in Korea : a multicenter study

We conducted a multicenter study to determine the clinical and microbiological characteristics of health care-associated (HCA) cellulitis in Korea. We retrospectively reviewed the medical records of patients who had been diagnosed with community-onset cellulitis. Of the 2208 cellulitis patients, 232 (10.5%) had HCA cellulitis, 1243 (56.3%) patients were hospitalized, and 15 (0.7%) died in hospital. Compared with community-acquired (CA) cellulitis, patients with HCA cellulitis were older and more frequently presented with comorbidity and septic shock. A total of 355 microorganisms were isolated from 314 patients (14.2%). Staphylococcus aureus (134 isolates) was the most common organism, followed by Streptococcus spp. (86 isolates) and Gram-negative fermenters (58 isolates). Methicillin-resistant S. aureus (MRSA) accounted for 29.1% (39/134) of S. aureus infections. None of the Gram-negative fermenters were resistant to carbapenem. The antibiotic susceptibility pattern of isolated microorganisms was not different between HCA and CA cellulitis. In patients with HCA cellulitis, S. aureus (11.2% [26/232] vs. 5.5% [108/1976], p = 0.001), including MRSA (4.3% [10/232] vs. 1.5% [29/1976], p = 0.003) and Gram-negative fermenters (6.0% [14/232] vs. 2.3% [44/1976], p = 0.002), were more common causative organisms than in CA-cellulitis patients. Age ≥ 65 years, septic shock, and HCA infection were statistically significant factors associated with in-hospital mortality.

Medienart:

E-Artikel

Erscheinungsjahr:

2019

Erschienen:

2019

Enthalten in:

Zur Gesamtaufnahme - volume:38

Enthalten in:

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 38(2019), 3 vom: 24. März, Seite 545-552

Sprache:

Englisch

Beteiligte Personen:

Park, Seong Yeon [VerfasserIn]
Kim, Tark [VerfasserIn]
Choi, Seong-Ho [VerfasserIn]
Jung, Jiwon [VerfasserIn]
Yu, Shi Nae [VerfasserIn]
Hong, Hyo-Lim [VerfasserIn]
Kim, Yong Kyun [VerfasserIn]
Park, Se Yoon [VerfasserIn]
Song, Eun Hee [VerfasserIn]
Park, Ki-Ho [VerfasserIn]
Cho, Oh-Hyun [VerfasserIn]
Choi, Sang Ho [VerfasserIn]
Kwak, Yee Gyung [VerfasserIn]
and the Korean SSTI (Skin and Soft Tissue Infection) Study Group [VerfasserIn]

Links:

Volltext

Themen:

Anti-Bacterial Agents
Cellulitis
Health care–associated infection
Journal Article
Multicenter Study
Staphylococcus aureus

Anmerkungen:

Date Completed 12.09.2019

Date Revised 25.02.2020

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1007/s10096-018-03456-0

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM293079463