Impact of health care-associated community-onset cellulitis in Korea : a multicenter study
We conducted a multicenter study to determine the clinical and microbiological characteristics of health care-associated (HCA) cellulitis in Korea. We retrospectively reviewed the medical records of patients who had been diagnosed with community-onset cellulitis. Of the 2208 cellulitis patients, 232 (10.5%) had HCA cellulitis, 1243 (56.3%) patients were hospitalized, and 15 (0.7%) died in hospital. Compared with community-acquired (CA) cellulitis, patients with HCA cellulitis were older and more frequently presented with comorbidity and septic shock. A total of 355 microorganisms were isolated from 314 patients (14.2%). Staphylococcus aureus (134 isolates) was the most common organism, followed by Streptococcus spp. (86 isolates) and Gram-negative fermenters (58 isolates). Methicillin-resistant S. aureus (MRSA) accounted for 29.1% (39/134) of S. aureus infections. None of the Gram-negative fermenters were resistant to carbapenem. The antibiotic susceptibility pattern of isolated microorganisms was not different between HCA and CA cellulitis. In patients with HCA cellulitis, S. aureus (11.2% [26/232] vs. 5.5% [108/1976], p = 0.001), including MRSA (4.3% [10/232] vs. 1.5% [29/1976], p = 0.003) and Gram-negative fermenters (6.0% [14/232] vs. 2.3% [44/1976], p = 0.002), were more common causative organisms than in CA-cellulitis patients. Age ≥ 65 years, septic shock, and HCA infection were statistically significant factors associated with in-hospital mortality.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2019 |
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Erschienen: |
2019 |
Enthalten in: |
Zur Gesamtaufnahme - volume:38 |
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Enthalten in: |
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 38(2019), 3 vom: 24. März, Seite 545-552 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Park, Seong Yeon [VerfasserIn] |
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Links: |
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Themen: |
Anti-Bacterial Agents |
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Anmerkungen: |
Date Completed 12.09.2019 Date Revised 25.02.2020 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1007/s10096-018-03456-0 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM293079463 |
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520 | |a We conducted a multicenter study to determine the clinical and microbiological characteristics of health care-associated (HCA) cellulitis in Korea. We retrospectively reviewed the medical records of patients who had been diagnosed with community-onset cellulitis. Of the 2208 cellulitis patients, 232 (10.5%) had HCA cellulitis, 1243 (56.3%) patients were hospitalized, and 15 (0.7%) died in hospital. Compared with community-acquired (CA) cellulitis, patients with HCA cellulitis were older and more frequently presented with comorbidity and septic shock. A total of 355 microorganisms were isolated from 314 patients (14.2%). Staphylococcus aureus (134 isolates) was the most common organism, followed by Streptococcus spp. (86 isolates) and Gram-negative fermenters (58 isolates). Methicillin-resistant S. aureus (MRSA) accounted for 29.1% (39/134) of S. aureus infections. None of the Gram-negative fermenters were resistant to carbapenem. The antibiotic susceptibility pattern of isolated microorganisms was not different between HCA and CA cellulitis. In patients with HCA cellulitis, S. aureus (11.2% [26/232] vs. 5.5% [108/1976], p = 0.001), including MRSA (4.3% [10/232] vs. 1.5% [29/1976], p = 0.003) and Gram-negative fermenters (6.0% [14/232] vs. 2.3% [44/1976], p = 0.002), were more common causative organisms than in CA-cellulitis patients. Age ≥ 65 years, septic shock, and HCA infection were statistically significant factors associated with in-hospital mortality | ||
650 | 4 | |a Journal Article | |
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650 | 4 | |a Cellulitis | |
650 | 4 | |a Health care–associated infection | |
650 | 4 | |a Staphylococcus aureus | |
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700 | 1 | |a Kim, Tark |e verfasserin |4 aut | |
700 | 1 | |a Choi, Seong-Ho |e verfasserin |4 aut | |
700 | 1 | |a Jung, Jiwon |e verfasserin |4 aut | |
700 | 1 | |a Yu, Shi Nae |e verfasserin |4 aut | |
700 | 1 | |a Hong, Hyo-Lim |e verfasserin |4 aut | |
700 | 1 | |a Kim, Yong Kyun |e verfasserin |4 aut | |
700 | 1 | |a Park, Se Yoon |e verfasserin |4 aut | |
700 | 1 | |a Song, Eun Hee |e verfasserin |4 aut | |
700 | 1 | |a Park, Ki-Ho |e verfasserin |4 aut | |
700 | 1 | |a Cho, Oh-Hyun |e verfasserin |4 aut | |
700 | 1 | |a Choi, Sang Ho |e verfasserin |4 aut | |
700 | 1 | |a Kwak, Yee Gyung |e verfasserin |4 aut | |
700 | 0 | |a and the Korean SSTI (Skin and Soft Tissue Infection) Study Group |e verfasserin |4 aut | |
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