CE : Original Research: Midlife Hypertension and Hypercholesterolemia in Relation to Cognitive Function Later in Life in Black Women

: Purpose: This study sought to evaluate midlife hypertension and hypercholesterolemia in relation to cognitive function later in life among black women.

METHODS: Participants were drawn from the Nurses' Health Study and the Women's Health Study databases. In these studies, health professionals reported health information by questionnaire at baseline and at regular follow-up intervals, including diagnoses of hypertension, hypercholesterolemia, or both; and they completed telephone-based cognitive assessments later in life. Multivariable-adjusted linear regression models were used to estimate mean differences in global cognition and executive function scores, comparing women with and without a history of hypertension at midlife and women with and without a history of hypercholesterolemia at midlife.

RESULTS: Data for 363 black female health professionals were analyzed. Those with a history of hypertension or hypercholesterolemia at midlife did not have lower global cognition and executive function scores later in life compared with those without such a history, although there were trends in this direction.

CONCLUSION: In the study sample, a history of hypertension or hypercholesterolemia at midlife was not related to worse cognitive function in later life. But there was a suggestive pattern of trends that warrants further exploration in larger studies.

Medienart:

E-Artikel

Erscheinungsjahr:

2019

Erschienen:

2019

Enthalten in:

Zur Gesamtaufnahme - volume:119

Enthalten in:

The American journal of nursing - 119(2019), 2 vom: 01. Feb., Seite 22-30

Sprache:

Englisch

Beteiligte Personen:

Devore, Elizabeth [VerfasserIn]
Hall, Kathryn E [VerfasserIn]
Schernhammer, Eva S [VerfasserIn]
Grodstein, Francine [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Anmerkungen:

Date Completed 19.11.2019

Date Revised 07.12.2022

published: Print

Citation Status MEDLINE

doi:

10.1097/01.NAJ.0000553179.89954.bc

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM29268343X