Composition and Anti-inflammatory Activity of Essential Oil of Jatropha curcas
The chemical constituents and anti-inflammatory activity of the essential oil from the leaf of Jatropha curcas L (Euphorbiaceae) collected from Nigeria are reported. The analysis of the chemical constituents of the essential oil was achieved by using gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). All constituents of the essential oil, namely neophytadiene (35.8%), phytol (23.1%), trans-pinane (12.7%), 6,10,14-trimethyl-2- pentadecanone (12:3%) and citronellyl propanoate (11.2%), were present in significant amounts. The anti-inflammatory activity of the leaf oil was determined on Wistar rats using egg-albumin as phlogistic agent; significant inhibition (P< 0.05) was shown at a dose of 2%, v/v. Percentage inhibition of the anti- inflammation increased steadily to 76.6% in the 4th hour.
Medienart: |
Artikel |
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Erscheinungsjahr: |
2017 |
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Erschienen: |
2017 |
Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
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Enthalten in: |
Natural product communications - 12(2017), 3 vom: 06. März, Seite 439-440 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Adeosun, Tolulope E [VerfasserIn] |
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Themen: |
Anti-Inflammatory Agents |
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Anmerkungen: |
Date Completed 04.03.2019 Date Revised 04.03.2019 published: Print Citation Status MEDLINE |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM291798071 |
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520 | |a The chemical constituents and anti-inflammatory activity of the essential oil from the leaf of Jatropha curcas L (Euphorbiaceae) collected from Nigeria are reported. The analysis of the chemical constituents of the essential oil was achieved by using gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). All constituents of the essential oil, namely neophytadiene (35.8%), phytol (23.1%), trans-pinane (12.7%), 6,10,14-trimethyl-2- pentadecanone (12:3%) and citronellyl propanoate (11.2%), were present in significant amounts. The anti-inflammatory activity of the leaf oil was determined on Wistar rats using egg-albumin as phlogistic agent; significant inhibition (P< 0.05) was shown at a dose of 2%, v/v. Percentage inhibition of the anti- inflammation increased steadily to 76.6% in the 4th hour | ||
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700 | 1 | |a Lawal, Oladipupo A |e verfasserin |4 aut | |
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