Network-Based Drug Repositioning : Approaches, Resources, and Research Directions
The wealth of knowledge and omic data available in drug research allowed the rising of several computational methods in drug discovery field yielding a novel and exciting application called drug repositioning. Several computational methods try to make a high-level integration of all the knowledge in order to discover unknown mechanisms. In this chapter we present an in-depth review of data resources and computational models for drug repositioning.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2019 |
|---|---|
| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:1903 |
|---|---|
| Enthalten in: |
Methods in molecular biology (Clifton, N.J.) - 1903(2019) vom: 13., Seite 97-113 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Alaimo, Salvatore [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Drug repositioning |
|---|
| Anmerkungen: |
Date Completed 10.06.2019 Date Revised 13.06.2019 published: Print Citation Status MEDLINE |
|---|
| doi: |
10.1007/978-1-4939-8955-3_6 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM291773885 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM291773885 | ||
| 003 | DE-627 | ||
| 005 | 20231225071618.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2019 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/978-1-4939-8955-3_6 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n0972.xml |
| 035 | |a (DE-627)NLM291773885 | ||
| 035 | |a (NLM)30547438 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Alaimo, Salvatore |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Network-Based Drug Repositioning |b Approaches, Resources, and Research Directions |
| 264 | 1 | |c 2019 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 10.06.2019 | ||
| 500 | |a Date Revised 13.06.2019 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a The wealth of knowledge and omic data available in drug research allowed the rising of several computational methods in drug discovery field yielding a novel and exciting application called drug repositioning. Several computational methods try to make a high-level integration of all the knowledge in order to discover unknown mechanisms. In this chapter we present an in-depth review of data resources and computational models for drug repositioning | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Drug repositioning | |
| 650 | 4 | |a Drug-target interaction prediction | |
| 650 | 4 | |a Interaction networks | |
| 650 | 4 | |a Network-based drug repurposing | |
| 650 | 4 | |a Precision medicine | |
| 650 | 7 | |a Ligands |2 NLM | |
| 700 | 1 | |a Pulvirenti, Alfredo |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Methods in molecular biology (Clifton, N.J.) |d 1984 |g 1903(2019) vom: 13., Seite 97-113 |w (DE-627)NLM074849794 |x 1940-6029 |7 nnns |
| 773 | 1 | 8 | |g volume:1903 |g year:2019 |g day:13 |g pages:97-113 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/978-1-4939-8955-3_6 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 1903 |j 2019 |b 13 |h 97-113 | ||