1.7 μm wavelength tunable gain-switched fiber laser and its application to spectroscopic photoacoustic imaging
Recently demonstrated bond-selective photoacoustic (PA) imaging has revealed the importance of 1.7 μm laser sources. In this Letter, we demonstrate a gain-switched thulium-doped fiber laser with continuous tuning from 1690 to 1765 nm by using an electrically driven acousto-optical tunable filter. Micro-joule laser pulses with a shot-to-shot intensity variation of 1.6% and a pulse duration of 150 ns are obtained. The laser source is then harnessed to implement a PA microscopy system, of which the lateral resolution is estimated to be 15.6 μm by scanning the edge of a black tape. The PA spectra of butter, rapeseed oil, and adipose tissue are measured, and they show a consistent absorption peak of around 1720 nm. Photoacoustic microscopy imaging of the adipose tissue demonstrates a high optical absorption contrast of lipids and the superiority of the laser for spectroscopic PA detection.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2018 |
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| Erschienen: |
2018 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:43 |
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| Enthalten in: |
Optics letters - 43(2018), 23 vom: 01. Dez., Seite 5849-5852 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Li, Can [VerfasserIn] |
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| Links: |
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| Themen: |
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| Anmerkungen: |
Date Completed 17.12.2018 Date Revised 15.01.2019 published: Print Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1364/OL.43.005849 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM291308716 |
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| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a Recently demonstrated bond-selective photoacoustic (PA) imaging has revealed the importance of 1.7 μm laser sources. In this Letter, we demonstrate a gain-switched thulium-doped fiber laser with continuous tuning from 1690 to 1765 nm by using an electrically driven acousto-optical tunable filter. Micro-joule laser pulses with a shot-to-shot intensity variation of 1.6% and a pulse duration of 150 ns are obtained. The laser source is then harnessed to implement a PA microscopy system, of which the lateral resolution is estimated to be 15.6 μm by scanning the edge of a black tape. The PA spectra of butter, rapeseed oil, and adipose tissue are measured, and they show a consistent absorption peak of around 1720 nm. Photoacoustic microscopy imaging of the adipose tissue demonstrates a high optical absorption contrast of lipids and the superiority of the laser for spectroscopic PA detection | ||
| 650 | 4 | |a Journal Article | |
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| 700 | 1 | |a Gong, Xiaojing |e verfasserin |4 aut | |
| 700 | 1 | |a Kong, Cihang |e verfasserin |4 aut | |
| 700 | 1 | |a Luo, Zhichao |e verfasserin |4 aut | |
| 700 | 1 | |a Song, Liang |e verfasserin |4 aut | |
| 700 | 1 | |a Wong, Kenneth K Y |e verfasserin |4 aut | |
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