Nanotherapeutics for the Treatment of Cancer and Arthritis

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BACKGROUND: Nanotechnology is gaining significant attention worldwide for the treatment of complex diseases such as AIDS (acquired immune deficiency syndrome), cancer and rheumatoid arthritis. Nanomedicine is the application of nanotechnology used for diagnosis and treatment for the disease that includes the preservation and improvement of human health by covering an area such as drug delivery using nanocarriers, nanotheranostics and nanovaccinology. The present article provides an insight into several aspects of nanomedicine such as usages of multiple types of nanocarriers, their status, advantages and disadvantages with reference to cancer and rheumatoid arthritis.

METHODS: An extensive search was performed on the bibliographic database for research article on nanotechnology and nanomedicine along with looking deeply into the aspects of these diseases, and how all of them are co-related. We further combined all the necessary information from various published articles and briefed to provide the current status.

RESULTS: Nanomedicine confers a unique technology against complex diseases which includes early diagnosis, prevention, and personalized therapy. The most common nanocarriers used globally are liposomes, polymeric nanoparticles, dendrimers, metallic nanoparticles, magnetic nanoparticles, solid lipid nanoparticles, polymeric micelles and nanotubes among others.

CONCLUSION: Nanocarriers are used to deliver drugs and biomolecules like proteins, antibody fragments, DNA fragments, and RNA fragments as the base of cancer biomarkers.

Medienart:

E-Artikel

Erscheinungsjahr:

2019

Erschienen:

2019

Enthalten in:

Zur Gesamtaufnahme - volume:20

Enthalten in:

Current drug metabolism - 20(2019), 6 vom: 27., Seite 430-445

Sprache:

Englisch

Beteiligte Personen:

Patel, Pal [VerfasserIn]
Meghani, Nikita [VerfasserIn]
Kansara, Krupa [VerfasserIn]
Kumar, Ashutosh [VerfasserIn]

Links:

Volltext

Themen:

Breast cancer
Cancer
Head and neck cancer
Journal Article
Lipids
Liposomes
Micelles
Nanocarriers
Nanotechnology
Polymers
Review
Rheumatoid arthritis.

Anmerkungen:

Date Completed 06.01.2020

Date Revised 06.01.2020

published: Print

Citation Status MEDLINE

doi:

10.2174/1389200220666181127102720

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM291104797