Impact of hypobaric flight simulation on walking distance and oxygenation in COPD patients
Copyright © 2018 Elsevier B.V. All rights reserved..
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a disease that compromises fitness to fly.
OBJECTIVE: To investigate, whether hypobaric mid-distance flight simulation limits exercise endurance in COPD patients.
METHODS: Patients with COPD GOLD stages 2-4 were challenged by hypobaric flight simulation. Patients completed 6-minute walking distances before and after the simulation test. Pulse oximetry and Borg dyspnea scale were measured every 30 min during the test.
RESULTS: Thirty-five patients were included in the study. The distance of the 6-min walking exercise decreased from 343 ± 93 m to 308 ± 101 m (p < 0.0001). The oxygen saturation nadir for the whole group was 72.2% ± 9.1%. The Borg-dypnea-score did not correlate with oxygen desaturation (R-square 0.009, p > 0.05).
CONCLUSIONS: A 3-h hypobaric flight simulation compromises exercise endurance by 35 m or 10%. Hypoxia was well tolerated and more liberal recommendations might by justifiable since hypoxemia appears to be unrelated to dyspnea perception.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2019 |
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| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:260 |
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| Enthalten in: |
Respiratory physiology & neurobiology - 260(2019) vom: 01. Feb., Seite 1-7 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Dellweg, Dominic [VerfasserIn] |
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| Links: |
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| Themen: |
6-MIN walking test |
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| Anmerkungen: |
Date Completed 03.04.2019 Date Revised 03.04.2019 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.resp.2018.11.010 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM291078567 |
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| 245 | 1 | 0 | |a Impact of hypobaric flight simulation on walking distance and oxygenation in COPD patients |
| 264 | 1 | |c 2019 | |
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| 500 | |a Date Completed 03.04.2019 | ||
| 500 | |a Date Revised 03.04.2019 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2018 Elsevier B.V. All rights reserved. | ||
| 520 | |a BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a disease that compromises fitness to fly | ||
| 520 | |a OBJECTIVE: To investigate, whether hypobaric mid-distance flight simulation limits exercise endurance in COPD patients | ||
| 520 | |a METHODS: Patients with COPD GOLD stages 2-4 were challenged by hypobaric flight simulation. Patients completed 6-minute walking distances before and after the simulation test. Pulse oximetry and Borg dyspnea scale were measured every 30 min during the test | ||
| 520 | |a RESULTS: Thirty-five patients were included in the study. The distance of the 6-min walking exercise decreased from 343 ± 93 m to 308 ± 101 m (p < 0.0001). The oxygen saturation nadir for the whole group was 72.2% ± 9.1%. The Borg-dypnea-score did not correlate with oxygen desaturation (R-square 0.009, p > 0.05) | ||
| 520 | |a CONCLUSIONS: A 3-h hypobaric flight simulation compromises exercise endurance by 35 m or 10%. Hypoxia was well tolerated and more liberal recommendations might by justifiable since hypoxemia appears to be unrelated to dyspnea perception | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a 6-MIN walking test | |
| 650 | 4 | |a Altitude – respiration | |
| 650 | 4 | |a COPD | |
| 650 | 4 | |a Hypoxemia | |
| 650 | 4 | |a Oxygen desaturation | |
| 650 | 4 | |a Oxygen supplementation | |
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| 700 | 1 | |a Kerl, Jens |e verfasserin |4 aut | |
| 700 | 1 | |a Hoehn, Ekkehard |e verfasserin |4 aut | |
| 700 | 1 | |a Haidl, Peter |e verfasserin |4 aut | |
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