Urbanization and humidity shape the intensity of influenza epidemics in U.S. cities
Copyright © 2018, American Association for the Advancement of Science..
Influenza epidemics vary in intensity from year to year, driven by climatic conditions and by viral antigenic evolution. However, important spatial variation remains unexplained. Here we show predictable differences in influenza incidence among cities, driven by population size and structure. Weekly incidence data from 603 cities in the United States reveal that epidemics in smaller cities are focused on shorter periods of the influenza season, whereas in larger cities, incidence is more diffuse. Base transmission potential estimated from city-level incidence data is positively correlated with population size and with spatiotemporal organization in population density, indicating a milder response to climate forcing in metropolises. This suggests that urban centers incubate critical chains of transmission outside of peak climatic conditions, altering the spatiotemporal geometry of herd immunity.
| Errataetall: |
CommentIn: Science. 2018 Oct 5;362(6410):29-30. - PMID 30287649 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2018 |
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| Erschienen: |
2018 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:362 |
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| Enthalten in: |
Science (New York, N.Y.) - 362(2018), 6410 vom: 05. Okt., Seite 75-79 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Dalziel, Benjamin D [VerfasserIn] |
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| Links: |
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| Themen: |
Antigens, Viral |
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| Anmerkungen: |
Date Completed 09.01.2019 Date Revised 25.02.2020 published: Print CommentIn: Science. 2018 Oct 5;362(6410):29-30. - PMID 30287649 Citation Status MEDLINE |
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| doi: |
10.1126/science.aat6030 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM289230403 |
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| 245 | 1 | 0 | |a Urbanization and humidity shape the intensity of influenza epidemics in U.S. cities |
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| 500 | |a CommentIn: Science. 2018 Oct 5;362(6410):29-30. - PMID 30287649 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2018, American Association for the Advancement of Science. | ||
| 520 | |a Influenza epidemics vary in intensity from year to year, driven by climatic conditions and by viral antigenic evolution. However, important spatial variation remains unexplained. Here we show predictable differences in influenza incidence among cities, driven by population size and structure. Weekly incidence data from 603 cities in the United States reveal that epidemics in smaller cities are focused on shorter periods of the influenza season, whereas in larger cities, incidence is more diffuse. Base transmission potential estimated from city-level incidence data is positively correlated with population size and with spatiotemporal organization in population density, indicating a milder response to climate forcing in metropolises. This suggests that urban centers incubate critical chains of transmission outside of peak climatic conditions, altering the spatiotemporal geometry of herd immunity | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, N.I.H., Extramural | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 7 | |a Antigens, Viral |2 NLM | |
| 700 | 1 | |a Kissler, Stephen |e verfasserin |4 aut | |
| 700 | 1 | |a Gog, Julia R |e verfasserin |4 aut | |
| 700 | 1 | |a Viboud, Cecile |e verfasserin |4 aut | |
| 700 | 1 | |a Bjørnstad, Ottar N |e verfasserin |4 aut | |
| 700 | 1 | |a Metcalf, C Jessica E |e verfasserin |4 aut | |
| 700 | 1 | |a Grenfell, Bryan T |e verfasserin |4 aut | |
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