Angiographic characteristics and long-term prognostic impact of coronary artery disease in survivors after sudden cardiac arrest with a non-diagnostic electrocardiogram

© 2018 Wiley Periodicals, Inc..

OBJECTIVES: Our purpose was to describe the prevalence, distribution, extension, and prognostic value of coronary artery disease (CAD) in patients resuscitated from sudden cardiac arrest (SCA) with non-diagnostic electrocardiogram (ECG).

BACKGROUND: The impact of CAD and the indication for cardiac catheterization (CC) in patients resuscitated from SCA with non-diagnostic ECG are uncertain.

METHODS: We included prospectively and consecutively 545 patients resuscitated from SCA with at least one CC during hospitalization. From them, 203 patients with a non-diagnostic ECG formed our study population. Patients were followed-up 5 years after discharge.

RESULTS: Overall, 125 (61.6%) patients had significant CAD, and at least one acute culprit lesion was found in 25 (12.4%). Regarding the burden and complexity of CAD, 78 (38.4%) patients had a CAD Prognostic Index of 0 and a SYNTAX score of 0. There was higher 5-year mortality only in patients with very high burden of CAD: three vessels with severe stenosis (P = 0.015) and CAD Prognostic Index Score ≥ 56 (P < 0.001). Tertiles of SYNTAX score did not predict higher 5-year mortality.

CONCLUSIONS: In survivors from SCA with a non-diagnostic ECG, significant CAD is highly prevalent. SYNTAX score was not associated with a different long-term prognosis in this patient population. Patients with severe disease in the three main coronary vessels and patients with higher (≥56) CAD Prognostic Index Score had a worse long-term prognosis.

Medienart:

E-Artikel

Erscheinungsjahr:

2019

Erschienen:

2019

Enthalten in:

Zur Gesamtaufnahme - volume:93

Enthalten in:

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions - 93(2019), 1 vom: 01. Jan., Seite 9-15

Sprache:

Englisch

Beteiligte Personen:

Nogales-Romo, María Teresa [VerfasserIn]
Ferrera, Carlos [VerfasserIn]
Salinas, Pablo [VerfasserIn]
Martínez-Losas, Pedro [VerfasserIn]
Nombela-Franco, Luis [VerfasserIn]
Núñez-Gil, Iván Javier [VerfasserIn]
Noriega, Francisco Javier [VerfasserIn]
Del Trigo, María [VerfasserIn]
Gonzalo, Nieves [VerfasserIn]
Jiménez-Quevedo, Pilar [VerfasserIn]
Escaned, Javier [VerfasserIn]
Fernández-Ortiz, Antonio [VerfasserIn]
Macaya, Carlos [VerfasserIn]
Viana-Tejedor, Ana [VerfasserIn]

Links:

Volltext

Themen:

ACS/NSTEMI
Coronary angiography
Coronary artery disease
Journal Article
Multicenter Study
Observational Study

Anmerkungen:

Date Completed 20.01.2020

Date Revised 20.01.2020

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1002/ccd.27713

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM289160324