Multiple myeloma with pathologically proven skull plasmacytoma after a mild head injury : Case report

RATIONALE: MM is a malignant tumor originating from the plasma cells of the bone marrow. Central nervous system myelomatosis is very rare and may be a complication of MM.

PATIENT CONCERNS: A 60-year-old man presented with a slowly growing soft mass at his right frontal scalp after a mild head injury 6 months ago.

DIAGNOSES: Neuroradiological examinations revealed a solid intracranial-extracranial mass with an osteolytic lesion in the skull. Histopathological examination showed skull plasmacytoma, and postoperative examinations revealed multiple myeloma.

INTERVENTIONS: The tumor was completely removed and the skull defect repaired with the titanium mesh. Then, chemotherapy was initiated after surgery with bortezomib and dexamethasone.

OUTCOMES: The patient received eight chemotherapies within one year after surgery.

LESSONS: Despite a history of head injury, a differential diagnosis should be kept in mind during the diagnosis of solid intracranial-extracranial masses, especially in the presence of osteolytic skull at the lesioned site.

Medienart:

E-Artikel

Erscheinungsjahr:

2018

Erschienen:

2018

Enthalten in:

Zur Gesamtaufnahme - volume:97

Enthalten in:

Medicine - 97(2018), 39 vom: 15. Sept., Seite e12327

Sprache:

Englisch

Beteiligte Personen:

Yang, Wenzhen [VerfasserIn]
Zheng, Jing [VerfasserIn]
Li, Ruihao [VerfasserIn]
Ren, Haijun [VerfasserIn]
Hou, Boru [VerfasserIn]
Zhao, Zhiyong [VerfasserIn]
Wang, Dengfeng [VerfasserIn]
Wang, Gang [VerfasserIn]
Liu, Jixing [VerfasserIn]
Yan, Guizhong [VerfasserIn]
Wang, Dong [VerfasserIn]
Zhang, Xinding [VerfasserIn]

Links:

Volltext

Themen:

69G8BD63PP
7S5I7G3JQL
Antineoplastic Agents
Bortezomib
Case Reports
Dexamethasone
Journal Article

Anmerkungen:

Date Completed 12.10.2018

Date Revised 21.03.2022

published: Print

Citation Status MEDLINE

doi:

10.1097/MD.0000000000012327

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM289140846