Multiple myeloma with pathologically proven skull plasmacytoma after a mild head injury : Case report
RATIONALE: MM is a malignant tumor originating from the plasma cells of the bone marrow. Central nervous system myelomatosis is very rare and may be a complication of MM.
PATIENT CONCERNS: A 60-year-old man presented with a slowly growing soft mass at his right frontal scalp after a mild head injury 6 months ago.
DIAGNOSES: Neuroradiological examinations revealed a solid intracranial-extracranial mass with an osteolytic lesion in the skull. Histopathological examination showed skull plasmacytoma, and postoperative examinations revealed multiple myeloma.
INTERVENTIONS: The tumor was completely removed and the skull defect repaired with the titanium mesh. Then, chemotherapy was initiated after surgery with bortezomib and dexamethasone.
OUTCOMES: The patient received eight chemotherapies within one year after surgery.
LESSONS: Despite a history of head injury, a differential diagnosis should be kept in mind during the diagnosis of solid intracranial-extracranial masses, especially in the presence of osteolytic skull at the lesioned site.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2018 |
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Erschienen: |
2018 |
Enthalten in: |
Zur Gesamtaufnahme - volume:97 |
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Enthalten in: |
Medicine - 97(2018), 39 vom: 15. Sept., Seite e12327 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Yang, Wenzhen [VerfasserIn] |
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Links: |
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Themen: |
69G8BD63PP |
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Anmerkungen: |
Date Completed 12.10.2018 Date Revised 21.03.2022 published: Print Citation Status MEDLINE |
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doi: |
10.1097/MD.0000000000012327 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM289140846 |
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520 | |a RATIONALE: MM is a malignant tumor originating from the plasma cells of the bone marrow. Central nervous system myelomatosis is very rare and may be a complication of MM | ||
520 | |a PATIENT CONCERNS: A 60-year-old man presented with a slowly growing soft mass at his right frontal scalp after a mild head injury 6 months ago | ||
520 | |a DIAGNOSES: Neuroradiological examinations revealed a solid intracranial-extracranial mass with an osteolytic lesion in the skull. Histopathological examination showed skull plasmacytoma, and postoperative examinations revealed multiple myeloma | ||
520 | |a INTERVENTIONS: The tumor was completely removed and the skull defect repaired with the titanium mesh. Then, chemotherapy was initiated after surgery with bortezomib and dexamethasone | ||
520 | |a OUTCOMES: The patient received eight chemotherapies within one year after surgery | ||
520 | |a LESSONS: Despite a history of head injury, a differential diagnosis should be kept in mind during the diagnosis of solid intracranial-extracranial masses, especially in the presence of osteolytic skull at the lesioned site | ||
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700 | 1 | |a Zhang, Xinding |e verfasserin |4 aut | |
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