Short-term effectiveness of HIV care coordination among persons with recent HIV diagnosis or history of poor HIV outcomes

The New York City HIV Care Coordination Program (CCP) combines multiple evidence-based strategies to support persons living with HIV (PLWH) at risk for, or with a recent history of, poor HIV outcomes. We assessed the comparative effectiveness of the CCP by merging programmatic data on CCP clients with population-based surveillance data on all New York City PLWH. A non-CCP comparison group of similar PLWH who met CCP eligibility criteria was identified using surveillance data. The CCP and non-CCP groups were matched on propensity for CCP enrollment within four baseline treatment status groups (newly diagnosed or previously diagnosed and either consistently unsuppressed, inconsistently suppressed or consistently suppressed). We compared CCP to non-CCP proportions with viral load suppression at 12-month follow-up. Among the 13,624 persons included, 15∙3% were newly diagnosed; among the 84∙7% previously diagnosed, 14∙2% were consistently suppressed, 28∙9% were inconsistently suppressed, and 41∙6% were consistently unsuppressed in the year prior to baseline. At 12-month follow-up, 59∙9% of CCP and 53∙9% of non-CCP participants had viral load suppression (Relative Risk = 1.11, 95%CI:1.08-1.14). Among those newly diagnosed and those consistently unsuppressed at baseline, the relative risk of viral load suppression in the CCP versus non-CCP participants was 1.15 (95%CI:1.09-1.23) and 1.32 (95%CI:1.23-1.42), respectively. CCP exposure shows benefits over no CCP exposure for persons newly diagnosed or consistently unsuppressed, but not for persons suppressed in the year prior to baseline. We recommend more targeted case finding for CCP enrollment and increased attention to viral load suppression maintenance.

Medienart:

E-Artikel

Erscheinungsjahr:

2018

Erschienen:

2018

Enthalten in:

Zur Gesamtaufnahme - volume:13

Enthalten in:

PloS one - 13(2018), 9 vom: 24., Seite e0204017

Sprache:

Englisch

Beteiligte Personen:

Nash, Denis [VerfasserIn]
Robertson, McKaylee M [VerfasserIn]
Penrose, Kate [VerfasserIn]
Chamberlin, Stephanie [VerfasserIn]
Robbins, Rebekkah S [VerfasserIn]
Braunstein, Sarah L [VerfasserIn]
Myers, Julie E [VerfasserIn]
Abraham, Bisrat [VerfasserIn]
Kulkarni, Sarah [VerfasserIn]
Waldron, Levi [VerfasserIn]
Levin, Bruce [VerfasserIn]
Irvine, Mary K [VerfasserIn]

Links:

Volltext

Themen:

Anti-HIV Agents
Journal Article
Observational Study
Research Support, N.I.H., Extramural

Anmerkungen:

Date Completed 06.03.2019

Date Revised 29.04.2020

published: Electronic-eCollection

Citation Status MEDLINE

doi:

10.1371/journal.pone.0204017

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM288844815