Pulling a MAST1 on Cisplatin Resistance
Copyright © 2018 Elsevier Inc. All rights reserved..
In this issue of Cancer Cell, Jin and colleagues use a kinome-wide screen to identify MAST1 as a cause of cisplatin resistance. They demonstrate that this kinase is a novel activator of MEK1 and the MAPK cascade and that it can harness pathway output to block cisplatin-induced cell death.
| Errataetall: |
CommentOn: Cancer Cell. 2018 Aug 13;34(2):315-330.e7. - PMID 30033091 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2018 |
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| Erschienen: |
2018 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:34 |
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| Enthalten in: |
Cancer cell - 34(2018), 2 vom: 13. Aug., Seite 183-185 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Jaykumar, Ankita B [VerfasserIn] |
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| Links: |
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| Themen: |
Antineoplastic Agents |
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| Anmerkungen: |
Date Completed 30.05.2019 Date Revised 04.12.2021 published: Print CommentOn: Cancer Cell. 2018 Aug 13;34(2):315-330.e7. - PMID 30033091 Citation Status MEDLINE |
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| doi: |
10.1016/j.ccell.2018.07.010 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM287460754 |
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| 520 | |a In this issue of Cancer Cell, Jin and colleagues use a kinome-wide screen to identify MAST1 as a cause of cisplatin resistance. They demonstrate that this kinase is a novel activator of MEK1 and the MAPK cascade and that it can harness pathway output to block cisplatin-induced cell death | ||
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