Mortality rate of ICU patients with the Middle East Respiratory Syndrome - Coronavirus infection at King Fahad Hospital, Jeddah, Saudi Arabia

Copyright© by the National Institute of Public Health, Prague 2018..

OBJECTIVE: The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a novel coronavirus circulating in the Arabian Peninsula since September 2012. It leads to significant respiratory disease and among patients with co-morbidities is associated with high mortality. This research studied the mortality rate of MERS-CoV among intensive care unit (ICU) patients and the correlation of mortality with different co-morbidities.

METHODS: This was a retrospective observational study conducted at the Intensive Care Unit of the King Fahad Hospital, Jeddah, Saudi Arabia. Data was obtained through patient chart review.

RESULTS: The total sample consisted of 52 laboratory-confirmed MERS-CoV infection patients. 39 patients died, with a 75% case-fatality rate. Many patients had underlying co-morbidities, including diabetes mellitus (51.9%), hypertension (46.2%), and chronic renal disease (21.2%).

CONCLUSIONS: MERS-CoV ICU mortality remains markedly high due to a combination of factors; the disease process of MERS-CoV leads to multiple organ failure, particularly respiratory and renal failure.

Medienart:

E-Artikel

Erscheinungsjahr:

2018

Erschienen:

2018

Enthalten in:

Zur Gesamtaufnahme - volume:26

Enthalten in:

Central European journal of public health - 26(2018), 2 vom: 01. Juni, Seite 87-91

Sprache:

Englisch

Beteiligte Personen:

Garout, Mohammed A [VerfasserIn]
Jokhdar, Hani A A [VerfasserIn]
Aljahdali, Imad A [VerfasserIn]
Zein, Ahmed R [VerfasserIn]
Goweda, Reda A [VerfasserIn]
Hassan-Hussein, Abdurahman [VerfasserIn]

Links:

Volltext

Themen:

Intensive care units
Journal Article
Middle East Respiratory Syndrome Coronavirus
Mortality
Observational Study
Saudi Arabia

Anmerkungen:

Date Completed 20.12.2018

Date Revised 20.12.2018

published: Print

Citation Status MEDLINE

doi:

10.21101/cejph.a4764

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM287414663