Dietary Fat, Sugar Consumption, and Cardiorespiratory Fitness in Patients With Heart Failure With Preserved Ejection Fraction

Heart failure with preserved ejection fraction (HFpEF) is associated with obesity and, indirectly, with unhealthy diet. The role of dietary components in HFpEF is, however, largely unknown. In this study, the authors showed that in obese HFpEF patients, consumption of unsaturated fatty acids (UFA), was associated with better cardiorespiratory fitness, and UFA consumption correlated with better diastolic function and with greater fat-free mass. Similarly, mice fed with a high-fat diet rich in UFA and low in sugars had preserved myocardial function and reduced weight gain. Randomized clinical trials increasing dietary UFA consumption and reducing sugar consumption are warranted to confirm and expand our findings.

Medienart:

E-Artikel

Erscheinungsjahr:

2017

Erschienen:

2017

Enthalten in:

Zur Gesamtaufnahme - volume:2

Enthalten in:

JACC. Basic to translational science - 2(2017), 5 vom: 25. Okt., Seite 513-525

Sprache:

Englisch

Beteiligte Personen:

Carbone, Salvatore [VerfasserIn]
Canada, Justin M [VerfasserIn]
Buckley, Leo F [VerfasserIn]
Trankle, Cory R [VerfasserIn]
Billingsley, Hayley E [VerfasserIn]
Dixon, Dave L [VerfasserIn]
Mauro, Adolfo G [VerfasserIn]
Dessie, Sofanit [VerfasserIn]
Kadariya, Dinesh [VerfasserIn]
Mezzaroma, Eleonora [VerfasserIn]
Buzzetti, Raffaella [VerfasserIn]
Arena, Ross [VerfasserIn]
Van Tassell, Benjamin W [VerfasserIn]
Toldo, Stefano [VerfasserIn]
Abbate, Antonio [VerfasserIn]

Links:

Volltext

Themen:

Body composition
CPX, cardiopulmonary exercise testing
CRF, cardiorespiratory fitness
CV, cardiovascular
DT, deceleration time
Diet
FFM, fat-free mass
FM, fat mass
HF, heart failure
HFpEF, heart failure with preserved ejection fraction
Heart failure with preserved ejection fraction
IQR, interquartile range
Journal Article
MUFA, monounsaturated fatty acid
Obesity
PUFA, polyunsaturated fatty acid
SFA, saturated fatty acid
UFA, unsaturated fatty acid
Unsaturated fatty acids
Vo2, oxygen consumption

Anmerkungen:

Date Revised 01.10.2020

published: Electronic-eCollection

Citation Status PubMed-not-MEDLINE

doi:

10.1016/j.jacbts.2017.06.009

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM287020231