Management of diabetic ketoacidosis and hyperglycemic hyperosmolar state in adults
Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic syndrome (HHS) are two acute complications of diabetes associated with high mortality rate if not efficiently and effectively treated. Both entities are characterized by insulinopenia, hyperglycemia and dehydration. DKA and HHS are two serious complications of diabetes associated with significant mortality and a high healthcare costs. The overall DKA mortality in the US is less than 1%, but a rate higher than 5% is reported in the elderly and in patients with concomitant life-threatening illnesses. Mortality in patients with HHS is reported between 5% and 16%, which is about 10 times higher than the mortality in patients with DKA. Objectives of management include restoration circulatory volume and tissue perfusion, resolution of hyperglycemia, correction of electrolyte imbalance and increased ketogenesis.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2016 |
|---|---|
| Erschienen: |
2016 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:11 |
|---|---|
| Enthalten in: |
Expert review of endocrinology & metabolism - 11(2016), 2 vom: 01. März, Seite 177-185 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Anzola, Isabel [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Diabetic ketoacidosis |
|---|
| Anmerkungen: |
Date Revised 20.11.2019 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
|---|
| doi: |
10.1586/17446651.2016.1145049 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM286987929 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM286987929 | ||
| 003 | DE-627 | ||
| 005 | 20231225053007.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2016 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1586/17446651.2016.1145049 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n0956.xml |
| 035 | |a (DE-627)NLM286987929 | ||
| 035 | |a (NLM)30058870 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Anzola, Isabel |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Management of diabetic ketoacidosis and hyperglycemic hyperosmolar state in adults |
| 264 | 1 | |c 2016 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Revised 20.11.2019 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic syndrome (HHS) are two acute complications of diabetes associated with high mortality rate if not efficiently and effectively treated. Both entities are characterized by insulinopenia, hyperglycemia and dehydration. DKA and HHS are two serious complications of diabetes associated with significant mortality and a high healthcare costs. The overall DKA mortality in the US is less than 1%, but a rate higher than 5% is reported in the elderly and in patients with concomitant life-threatening illnesses. Mortality in patients with HHS is reported between 5% and 16%, which is about 10 times higher than the mortality in patients with DKA. Objectives of management include restoration circulatory volume and tissue perfusion, resolution of hyperglycemia, correction of electrolyte imbalance and increased ketogenesis | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Ketoacidosis | |
| 650 | 4 | |a diabetic ketoacidosis | |
| 650 | 4 | |a hospital | |
| 650 | 4 | |a hyperglycemia hyperosmolar state | |
| 650 | 4 | |a inpatient care | |
| 700 | 1 | |a Gomez, Patricia C |e verfasserin |4 aut | |
| 700 | 1 | |a Umpierrez, Guillermo E |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Expert review of endocrinology & metabolism |d 2006 |g 11(2016), 2 vom: 01. März, Seite 177-185 |w (DE-627)NLM191111503 |x 1744-8417 |7 nnns |
| 773 | 1 | 8 | |g volume:11 |g year:2016 |g number:2 |g day:01 |g month:03 |g pages:177-185 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1586/17446651.2016.1145049 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 11 |j 2016 |e 2 |b 01 |c 03 |h 177-185 | ||