Synthetic Cannabinoid use in a Case Series of Patients with Psychosis Presenting to Acute Psychiatric Settings : Clinical Presentation and Management Issues

BACKGROUND: Novel Psychoactive Substances (NPS) are a heterogeneous class of synthetic molecules including synthetic cannabinoid receptor agonists (SCRAs). Psychosis is associated with SCRAs use. There is limited knowledge regarding the structured assessment and psychometric evaluation of clinical presentations, analytical toxicology and clinical management plans of patients presenting with psychosis and SCRAs misuse.

METHODS: We gathered information regarding the clinical presentations, toxicology and care plans of patients with psychosis and SCRAs misuse admitted to inpatients services. Clinical presentations were assessed using the PANSS scale. Vital signs data were collected using the National Early Warning Signs tool. Analytic chemistry data were collected using urine drug screening tests for traditional psychoactive substances and NPS.

RESULTS: We described the clinical presentation and management plan of four patients with psychosis and misuse of SCRAs.

CONCLUSION: The formulation of an informed clinical management plan requires a structured assessment, identification of the index NPS, pharmacological interventions, increases in nursing observations, changes to leave status and monitoring of the vital signs. The objective from using these interventions is to maintain stable physical health whilst rapidly improving the altered mental state.

Medienart:

E-Artikel

Erscheinungsjahr:

2018

Erschienen:

2018

Enthalten in:

Zur Gesamtaufnahme - volume:8

Enthalten in:

Brain sciences - 8(2018), 7 vom: 14. Juli

Sprache:

Englisch

Beteiligte Personen:

Bonaccorso, Stefania [VerfasserIn]
Metastasio, Antonio [VerfasserIn]
Ricciardi, Angelo [VerfasserIn]
Stewart, Neil [VerfasserIn]
Jamal, Leila [VerfasserIn]
Rujully, Naasir-Ud-Dinn [VerfasserIn]
Theleritis, Christos [VerfasserIn]
Ferracuti, Stefano [VerfasserIn]
Ducci, Giuseppe [VerfasserIn]
Schifano, Fabrizio [VerfasserIn]

Links:

Volltext

Themen:

Antipsychotics
Journal Article
Mental health
NPS
NPS testing
Novel psychoactive substances
Nursing care
Physical health
Psychosis
SCRAs
Synthetic cannabinoids

Anmerkungen:

Date Revised 01.10.2020

published: Electronic

Citation Status PubMed-not-MEDLINE

doi:

10.3390/brainsci8070133

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM286527847